Abstract | PURPOSE: METHODS: One eye each of 15 New Zealand white rabbits was assigned to one of three groups. Eyes in group 1 received a vitreous injection of 1 unit of human plasmin (0.1 mL reconstituted in balanced salt solution) and 0.5 mL of SF6; eyes in group 2 received a vitreous injection of plasmin alone; eyes in group 3 received a vitreous injection of SF6 alone. Seven days after injection, all animals were monitored electroretinographically and killed, and the eyes were enucleated. After fixation, scanning electron microscopy was performed. RESULTS: In group 1 eyes, the retinal surface was smooth except for the vitreous base, which showed complete separation of the vitreous cortex from the retina, indicating PVD. In group 2 and 3 eyes, sparse collagen fibers remained on the retinal surface. CONCLUSION:
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Authors | T Hikichi, N Yanagiya, M Kado, J Akiba, A Yoshida |
Journal | Retina (Philadelphia, Pa.)
(Retina)
Vol. 19
Issue 1
Pg. 55-8
( 1999)
ISSN: 0275-004X [Print] United States |
PMID | 10048374
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Fibrinolysin
- Sulfur Hexafluoride
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Topics |
- Animals
- Drug Therapy, Combination
- Electroretinography
- Eye Diseases
(pathology, surgery)
- Fibrinolysin
(administration & dosage)
- Injections
- Male
- Microscopy, Electron, Scanning
- Ophthalmologic Surgical Procedures
(methods)
- Rabbits
- Retina
(physiology)
- Sulfur Hexafluoride
(administration & dosage)
- Vitreous Body
(drug effects, surgery, ultrastructure)
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