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Topoisomerase I Inhibitors

Compounds that inhibit the activity of DNA TOPOISOMERASE I.
Also Known As:
DNA Topoisomerase I Inhibitors; DNA Type 1 Topoisomerase Inhibitors; Inhibitors, Topoisomerase 1; Inhibitors, Topoisomerase I; Topoisomerase 1 Inhibitors
Networked: 151 relevant articles (17 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Pommier, Yves: 6 articles (09/2015 - 01/2003)
2. Cushman, Mark: 3 articles (02/2014 - 12/2003)
3. Soda, Hiroshi: 3 articles (11/2006 - 08/2003)
4. Nakamura, Yoichi: 3 articles (11/2006 - 08/2003)
5. Shiozawa, Ken: 3 articles (11/2006 - 08/2003)
6. Oka, Mikio: 3 articles (11/2006 - 08/2003)
7. Kohno, Shigeru: 3 articles (11/2006 - 08/2003)
8. Kitazaki, Takeshi: 3 articles (11/2006 - 08/2003)
9. Choy, Hak: 3 articles (06/2004 - 01/2002)
10. Cummings, Jeffrey: 3 articles (01/2004 - 02/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Colorectal Neoplasms (Colorectal Cancer)
3. Colonic Neoplasms (Colon Cancer)
4. Hepatocellular Carcinoma (Hepatoma)
5. Breast Neoplasms (Breast Cancer)

Related Drugs and Biologics

1. Topotecan (Hycamtin)
2. Camptothecin
3. irinotecan (Camptosar)
4. Fluorouracil (Carac)
5. tirapazamine (SR 4233)
6. Taxoids
7. Cisplatin (Platino)
8. Type I DNA Topoisomerases (Topoisomerase I)
9. gemcitabine
10. Etoposide (VP 16)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Bone Marrow Transplantation (Transplantation, Bone Marrow)
4. Aftercare (After-Treatment)
5. Combined Modality Therapy