|1.||Ferré-D'Amaré, Adrian R: 3 articles (09/2014 - 06/2007)|
|2.||Mulhbacher, Jérôme: 2 articles (10/2010 - 04/2010)|
|3.||Lafontaine, Daniel A: 2 articles (10/2010 - 04/2010)|
|4.||Kreuz, Sebastian: 1 article (10/2015)|
|5.||Gantner, Florian: 1 article (10/2015)|
|6.||Klauser, Benedikt: 1 article (10/2015)|
|7.||Strobel, Benjamin: 1 article (10/2015)|
|8.||Hartig, Jörg S: 1 article (10/2015)|
|9.||Lamla, Thorsten: 1 article (10/2015)|
|10.||Poel, Toni J: 1 article (09/2015)|
|1.||Dehydration (Water Stress)
09/02/2014 - "Replacement of Li(+) and Mg(2+) needed for growth of crystals of a tRNA-riboswitch-protein complex with Sr(2+), coupled with dehydration, dramatically improved the resolution limit (8.5-3.2 Å) and data quality, enabling structure determination. "
10/09/2012 - "Dehydration from conserved stem regions is fundamental for ligand-dependent conformational transition of the adenine-specific riboswitch."
09/01/2015 - "Novel riboswitch-binding flavin analog that protects mice against Clostridium difficile infection without inhibiting cecal flora."
01/01/2012 - "We demonstrate the utility of riboswitches, and for the first time show that riboswitches can be used to functionally control a bacterial gene that is critical to the ability of a pathogen to cause disease, during intracellular infection. "
01/01/2012 - "Riboswitch-mediated control of FTN_0818 rescued the growth of an FTN_0818 mutant in minimal medium and during macrophage infection. "
12/20/2011 - "Recent rational drug design efforts focused on select riboswitch classes have yielded a small number of candidate antibiotic compounds, including one active in a mouse model of Staphylococcus aureus infection. "
01/01/2015 - "We here provide methods used by our laboratory to characterize the riboswitch response to theophylline in reporter strains, recombinant organisms containing riboswitch-regulated endogenous genes, and in host cell infections. "
01/01/2014 - "Operon-2 was highly up-regulated upon corrinoid starvation both at the transcriptional (346-fold) and proteomic level (46-fold on average), in line with the presence of an upstream cobalamin riboswitch. "
01/01/2011 - "We also showed, by using riboswitches that activate transcription in conditions of tyrosine or methionine starvation, that the effect of transcriptional de-repression of the leuC construct on the accumulation of Leu(+) mutations was independent of selection. "
06/01/2007 - "In addition to these riboswitch structures, a solution NMR structure has been reported for a ribosensor that regulates heat shock genes in response to changes in temperature. "
01/01/2013 - "We show functional relevance of two 5' UTR elements: a RNA thermonsensor (C1_109596F) that may regulate translation of the major cold shock protein cspA, and a thi-box riboswitch (C1_2541934R) that may transcriptionally regulate a thiamine biosynthesis operon, thiCOGG. "
|5.||Bacterial Infections (Bacterial Infection)
04/01/2010 - "Particularly, the finding of this new guanine riboswitch target is crucial as community-acquired bacterial infections have recently started to emerge."
10/01/2010 - "Ribozymes and riboswitches are RNA-based therapeutic tools that are most often employed to knockdown gene expression and to inhibit bacterial infections, respectively. "
|1.||Transfer RNA (tRNA)
|2.||RNA (Ribonucleic Acid)
|4.||Catalytic RNA (Ribozymes)
|6.||5' Untranslated Regions (5' UTR)
|7.||Vitamin B 12 (Cyanocobalamin)