|1.||Iozzo, Renato V: 55 articles (12/2015 - 03/2002)|
|2.||Schaefer, Liliana: 16 articles (10/2015 - 03/2002)|
|3.||Owens, Rick T: 16 articles (04/2014 - 02/2005)|
|4.||Neill, Thomas: 12 articles (12/2015 - 12/2010)|
|5.||Seidler, Daniela G: 10 articles (05/2013 - 08/2004)|
|6.||Wight, Thomas N: 7 articles (04/2015 - 10/2002)|
|7.||Buraschi, Simone: 7 articles (04/2014 - 12/2010)|
|8.||Tredget, Edward E: 6 articles (08/2015 - 05/2011)|
|9.||Iozzo, R V: 6 articles (03/2015 - 10/2000)|
|10.||Postma, Dirkje S: 6 articles (10/2013 - 03/2005)|
11/01/2011 - "The best results were obtained when surgery was used in conjunction with decorin that reduced both the PVR score and fibrosis development significantly (p < 0.05). "
06/01/2011 - "Tissue-targeted AAV5-mediated decorin gene therapy is effective and safe for treating corneal fibrosis in vivo."
09/01/2003 - "However, when we blocked the fibrosis process with decorin, an antifibrosis agent, we improved the muscle healing. "
01/01/2014 - "The aim of this study was to investigate the anti-fibrosis effect and the possible underlying mechanisms of decorin. "
06/01/2011 - "This study tested a hypothesis that tissue-selective targeted decorin gene therapy delivered to the stroma with adeno-associated virus serotype 5 (AAV5) inhibits corneal fibrosis in vivo without significant side effects. "
05/01/2013 - "In this article, we summarize recent studies of decorin in cancer and discuss decorin's therapeutic and prognostic value."
05/01/2013 - "More recent studies show that decorin plays important roles during tumor development and progression and is a potential cancer therapeutic agent. "
03/01/2011 - "Studies have linked decorin dysregulation to delayed tissue healing in patients with various diseases including cancer. "
07/01/2008 - "Thus, decorin is likely to possess a suppressive effect on human tumor angiogenesis in vivo, as previously described by studies using different experimental models. "
06/01/2008 - "Decorin is a major extracellular matrix protein which has become the focus of various cancer studies. "
10/01/2013 - "This study assessed the potential of highly purified (Stro-1(+)) human mesenchymal precursor cells (hMPCs) in combination with the anti-scarring protein decorin to repair the injured spinal cord (SC). "
08/01/2015 - "Reduced decorin synthesis is associated with dermal scarring, and increased decorin expression appears to reduce scar tissue formation. "
09/15/2014 - "Here, we discuss the potential of using Decorin to antagonise scarring in the central nervous system. "
08/25/2013 - "Recombinant decorin suppresses inflammatory reactions, inhibits glial scar formation, and promotes axonal growth. "
09/01/2012 - "Deep dermal fibroblasts refractory to migration and decorin-induced apoptosis contribute to hypertrophic scarring."
|4.||Neoplasm Metastasis (Metastasis)
01/01/2012 - "This study indicates that high expression of Decorin is associated with lymph node metastasis (p<0.001), higher number of positive lymph nodes (p<0.0001) and worse overall survival (p = 0.01). "
05/01/2015 - "We also showed that overexpression of decorin could inhibit NSCLC cell lines proliferation and metastasis. "
05/01/2015 - "Via ectopic expression analyses and Western blot, the roles of decorin in proliferation, metastasis, and the underline mechanism for decorin expression were further explored. "
07/01/2013 - "Down-regulation of decorin expression and the presence of lymph node metastasis were adverse factor independently affecting overall survival in OSCC."
07/01/2013 - "Lymph node metastasis and reduced decorin expression independently correlated with overall survival in OSCC. "
|5.||Breast Neoplasms (Breast Cancer)
12/01/2015 - "Our in vitro studies showed that Ad.dcn produced high levels of viral replication and the decorin protein in the breast tumor cells. "
01/01/2013 - "Our study also shows that transduction of decorin in decorin-negative human breast cancer cells markedly modulates the growth pattern of these cells."
11/01/2015 - "Prognostic value of stromal decorin expression in patients with breast cancer: a meta-analysis."
01/01/2014 - "Periostin suppression induces decorin secretion leading to reduced breast cancer cell motility and invasion."
01/01/2013 - "We also examined the effect of decorin transduction on the behavior of cultured human breast cancer MCF7 cells. "
|2.||Transforming Growth Factor beta (TGF-beta)
|3.||Messenger RNA (mRNA)
|8.||Transforming Growth Factor beta1 (TGF beta 1)
|10.||Insulin-Like Growth Factor I (IGF-1)
|1.||Heterologous Transplantation (Xenotransplantation)
|4.||Homologous Transplantation (Allograft)