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Class I Phosphatidylinositol 3-Kinases

A phosphatidylinositol 3-kinase subclass that includes enzymes with a specificity for 1-phosphatidylinositol, 1-phosphatidylinositol 4-phosphate, and 1-phosphatidylinositol 4,5-bisphosphate. Members of this enzyme subclass are activated by cell surface receptors and occur as heterodimers of enzymatic and regulatory subunits.
Also Known As:
Class I Phosphatidylinositol 3-Kinase; Class I Phosphatidylinositol 3 Kinase; Class I Phosphatidylinositol 3 Kinases; Phosphatidylinositol 3 Kinase, Class I; Phosphatidylinositol 3-Kinase, Class I
Networked: 19 relevant articles (0 outcomes, 6 trials/studies)

Bio-Agent Context: Research Results

Experts

1. O'Brien, Carol: 2 articles (01/2014 - 07/2010)
2. Lackner, Mark R: 2 articles (01/2014 - 07/2010)
3. Zhao, Kui: 2 articles (05/2013 - 10/2009)
4. Zhu, Bao-Song: 2 articles (05/2013 - 10/2009)
5. Xing, Chun-Gen: 2 articles (05/2013 - 10/2009)
6. Prior, Wei Wei: 2 articles (11/2011 - 07/2010)
7. Sampath, Deepak: 2 articles (11/2011 - 07/2010)
8. Gong, Zhiyuan: 1 article (10/2015)
9. Lu, Kaihui: 1 article (10/2015)
10. Cui, Jianzhou: 1 article (10/2015)

Related Diseases

1. Neoplasms (Cancer)
2. Stomach Neoplasms (Stomach Cancer)
3. Breast Neoplasms (Breast Cancer)
4. Colitis
5. Starvation

Related Drugs and Biologics

1. 2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- one
2. Sirolimus (Rapamycin)
3. Dextrans (Dextran)
4. erlotinib (CP 358,774)
5. sodium sulfate (sodium bisulfate)
6. Phosphotransferases (Kinase)
7. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
8. Dual-Specificity Phosphatases
9. MicroRNAs (MicroRNA)
10. Interleukin-10 (Interleukin 10)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)