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Capsule Opacification

Clouding or loss of transparency of the posterior lens capsule, usually following CATARACT extraction.
Also Known As:
Capsule Opacifications; Opacification, Capsule; Opacifications, Capsule
Networked: 598 relevant articles (18 outcomes, 71 trials/studies)

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Disease Context: Research Results

Related Diseases

1. Cataract (Cataracts)
2. Inflammation
3. Glaucoma
4. Macular Edema
5. Macular Degeneration (Age-Related Maculopathy)

Experts

1. Findl, Oliver: 27 articles (12/2013 - 07/2002)
2. Menapace, Rupert: 23 articles (05/2015 - 07/2002)
3. Buehl, Wolf: 22 articles (01/2013 - 07/2002)
4. Sacu, Stefan: 18 articles (04/2009 - 07/2002)
5. Georgopoulos, Michael: 11 articles (06/2014 - 07/2002)
6. Vasavada, Abhay R: 10 articles (09/2015 - 05/2004)
7. Werner, Liliana: 10 articles (01/2015 - 01/2002)
8. Boyce, James: 9 articles (05/2013 - 04/2004)
9. Apple, David J: 9 articles (04/2005 - 01/2002)
10. Apple, D J: 9 articles (10/2001 - 01/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Capsule Opacification:
1. SiliconesIBA
2. NeodymiumIBA
3. Fluorouracil (Carac)FDA LinkGeneric
4. Cyclosporine (Ciclosporin)FDA LinkGeneric
5. Heparin (Liquaemin)FDA LinkGeneric
6. styrene-ethylene-butylene-styrene-block copolymerIBA
7. 1-phenyl-3,3-dimethyltriazene (PDT)IBA
8. Carbon MonoxideIBA
9. tranilast (N 5')IBA
10. Immunotoxins (Immunotoxin)IBA

Therapies and Procedures

1. Intraocular Lenses (Intraocular Lens)
2. Solid-State Lasers
3. Lenses
01/01/2014 - "People with accommodative lenses were more likely to be spectacle-independent but the estimate was very uncertain (risk ratio (RR) 8.18; 95% CI 0.47 to 142.62, 1 study, 40 people, very low quality evidence).More cases of posterior capsule opacification (PCO) were seen in accommodative lenses but the effect of the lenses on PCO was uncertain (Peto odds ratio (OR) 2.12; 95% CI 0.45 to 10.02, 91 people, 2 studies, low quality evidence). "
01/01/2009 - "Inclusion CriteriaExclusion Criteriaadult patients with age-related cataractssystematic reviews, randomized controlled trials (RCTs) distance visual acuity (best corrected distance visual acuity), near visual acuity (best distance corrected near visual acuity) contrast sensitivity, depth of field, glare, quality of life, visual function, spectacle dependence, posterior capsule opacification.studies with fewer than 20 eyesIOLs for non-age related cataractsIOLs for presbyopiastudies with a mean follow-up <6monthsstudies reporting insufficient data for analysis COMPARISONS OF INTEREST: The primary comparison of interest was accommodative vs. multifocal vs. monofocal lenses. "
01/01/1988 - "[Experimental study of posterior capsule opacification and optic decentering of various posterior chamber lenses following intercapsular implantation]."
01/01/2008 - "The effect of hydrophobic acrylic foldable lenses on preventing anterior and posterior capsule opacification is mainly a result of the acrylic hydrophobic biomaterial."
05/01/2004 - "Posterior capsule opacification after implantation of CeeOn Edge 911A, PhacoFlex SI-40NB, and AcrySof MA60BM lenses: one-year results of an intraindividual comparison multicenter study."
4. Capsulorhexis
5. Intraocular Lens Implantation