|5.||Macular Degeneration (Age-Related Maculopathy)
|1.||Findl, Oliver: 27 articles (12/2013 - 07/2002)|
|2.||Menapace, Rupert: 23 articles (05/2015 - 07/2002)|
|3.||Buehl, Wolf: 22 articles (01/2013 - 07/2002)|
|4.||Sacu, Stefan: 18 articles (04/2009 - 07/2002)|
|5.||Georgopoulos, Michael: 11 articles (06/2014 - 07/2002)|
|6.||Vasavada, Abhay R: 10 articles (09/2015 - 05/2004)|
|7.||Werner, Liliana: 10 articles (01/2015 - 01/2002)|
|8.||Boyce, James: 9 articles (05/2013 - 04/2004)|
|9.||Apple, David J: 9 articles (04/2005 - 01/2002)|
|10.||Apple, D J: 9 articles (10/2001 - 01/2000)|
01/01/2015 - "Round-edged silicone IOLs may also retard posterior capsule opacification formation, though not as much as sharp-edged IOLs. "
03/01/2013 - "Long-term (after 4 weeks) complications included migration of silicone oil into the anterior chamber, posterior capsule opacification, and decentered IOL. "
08/01/2010 - "The silicone refractive multifocal IOL provided good and stable distance and near visual acuities over the 4-year follow-up, even though it was anticipated that slight posterior capsule opacification would affect near vision. "
05/01/2007 - "The additional posterior capsule opacification showed a distinct pattern and localisation when compared to the use of 5000 mPas-silicone oil as tamponade."
12/01/2002 - "Posterior capsule opacification developed in 48 eyes (34.2%), with the highest incidence in the silicone group. "
11/01/2005 - "Effect of anterior capsule polishing on posterior capsule opacification and neodymium:YAG capsulotomy rates: three-year randomized trial."
12/01/2001 - "To study the natural evolution of Elschnig pearl posterior capsule opacification (PCO) after neodymium:YAG posterior capsulotomy. "
08/01/2012 - "We report a case of progressive capsule membrane growth 4 months after neodymium:YAG capsulotomy for posterior capsule opacification. "
06/01/2011 - "The Evaluation of Posterior Capsule Opacification (EPCO) area, EPCO score, and neodymium:YAG (Nd:YAG) capsulotomy rates were compared using digital photographs. "
11/01/2010 - "None of the 20 eyes (20.0%) with posterior capsule opacification required neodymium:YAG capsulotomy. "
|3.||Fluorouracil (Carac)FDA LinkGeneric
01/01/2002 - "To evaluate the efficacy of an intracapsular ring releasing 5-fluorouracil (5-FU) in preventing posterior capsule opacification (PCO) in rabbit eyes. "
03/01/2013 - "The study aimed to prepare a new type intra ocular lens (IOL), in which 5-Fu, as an antimetabolite drug, could be sustained released to prevent posterior capsule opacification (PCO), and evaluate its efficacy and safety in vitro and in vivo. "
01/01/2002 - "Intracapsular ring sustained 5-fluorouracil delivery system for the prevention of posterior capsule opacification in rabbits: a histological study."
01/01/1996 - "MC and 5-FU could be a promising alternative in the prevention of posterior capsule opacification."
01/01/1990 - "Inhibition of posterior capsule opacification by 5-fluorouracil in rabbits."
|4.||Cyclosporine (Ciclosporin)FDA LinkGeneric
01/01/2008 - "On clinical assessment, cyclosporin A was significantly effective in preventing posterior capsule opacification compared with controls (P = 0.0045). "
01/01/2008 - "The preliminary results indicate that cyclosporin A is effective in suppressing posterior capsule opacification in rabbits, yet requires further investigation."
05/01/2015 - "The purpose of this study was to determine the Cyclosporine A (CsA) dose and minimum drug delivery time needed to prevent posterior capsule opacification (PCO) in an ex vivo canine model and evaluate the mechanism of CsA-induced cell death. "
01/01/2008 - "Cyclosporin effectively inhibits posterior capsule opacification after phacoemulsification in rabbits: a preliminary study."
01/01/2008 - "To evaluate whether cyclosporin A prevents or reduce posterior capsule opacification after phacoemulsification surgery in rabbit eyes. "
|5.||Heparin (Liquaemin)FDA LinkGeneric
07/01/2015 - "Prospective Randomized Intraindividual Comparison of Posterior Capsule Opacification After Implantation of an IOL With and Without Heparin Surface Modification."
05/01/1993 - "The incidence of posterior capsule opacification was greater in the heparin-surface-modified group than in the surface-passivated and regular groups, but the difference was not statistically significant."
07/01/2015 - "To compare posterior capsule opacification (PCO) of a hydrophobic acrylic heparin surface modified intraocular lens (HSM-IOL) and an uncoated IOL (UC-IOL) 1 year after implantation. "
10/01/2000 - "To study the efficacy of using a primary posterior capsulorhexis with optic capture and intracameral heparin in preventing secondary posterior capsule opacification, in paediatric cataract surgery. "
05/01/1993 - "Incidence of posterior capsule opacification in eyes with exfoliation syndrome and heparin-surface-modified intraocular lenses."
11/01/2010 - "The incidence of symptomatic posterior capsule opacification with the Rayner C-flex IOL is low."
02/01/2007 - "To compare the rate of posterior capsule opacification (PCO) with the single-piece hydrophilic acrylic foldable Rayner Centerflex 570H intraocular lens (IOL), which has a sharp optic edge design excluding the optic-haptic junction, and the Rayner C-flex 570C IOL, which has an improved 360-degree sharp edge. "
11/01/2010 - "The aim of the study was to evaluate the incidence of symptomatic posterior capsule opacification requiring Nd:YAG capsulotomy in patients who underwent cataract extraction and implantation of the Rayner C-flex 570C intraocular lens (IOL) (Rayner Intraocular Lens, Ltd., Sussex, UK). "
01/01/2015 - "To compare posterior capsule opacification (PCO) degree and visual functions after phacoemulsification in eyes implanted with 360-degree square edge hydrophilic acrylic intraocular lens (IOL) (570C C-flex, Rayner) and sharp edge hydrophobic acrylic IOL (Sensar AR40e, AMO) in diabetic patients. "
05/01/2002 - "The present study aimed to determine whether PDT with BCA is also effective in destroying LECs in the capsular bag in vivo and could therefore be a strategy for prevention of posterior capsule opacification (PCO). "
05/01/2002 - "We investigated the in vivo effect of photodynamic therapy (PDT) using rose bengal on the development of posterior capsule opacification (PCO). "
09/01/2000 - "Based on best-corrected visual acuity of 20/40 or worse without co-existing pathology, the 4-year incidence of posterior capsule opacification was 13.5%. "
10/01/1999 - "An anterior eye segment analysis system (EAS 1000, Nidek Co., Ltd.) was used to evaluate the degree of fibrous posterior capsule opacification (PCO) 1 week and 1 and 3 months after surgery. "
01/01/2012 - "Good outcome was significantly related to urban residence, presence of an intraocular lens and absence of ocular co-morbidities or posterior capsule opacification. "
03/01/2009 - "Other causes included posterior capsule opacification 7 (18.4%) eyes, preexisting ocular co-morbidity such as glaucoma, optic atrophy and maculopathy 6 (15.9%) eyes. "
|9.||tranilast (N 5')IBA
07/01/2001 - "[Effect of different concentrations of tranilast on posterior capsule opacification]."
12/01/2007 - "Safety and efficacy of intracapsular tranilast microspheres in experimental posterior capsule opacification."
01/01/2005 - "A final best corrected visual acuity of 0.5 or better was achieved in all eyes Postoperative complications included posterior capsule opacification (n = 5), glaucoma (n = 1), and cystoid macular edema (n = 1). "
07/01/2001 - "To evaluate the effect of different concentrations(0.5, 1.0, 2.0%) of tranilast eyedrops in preventing fibrous posterior capsule opacification (PCO) in rabbits. "
10/01/1999 - "Effect of tranilast eyedrops in preventing posterior capsule opacification: preliminary report."
08/01/2006 - "The successful cloning and expression of DT(389)-hbFGF immunotoxin lay a foundation for accelerating lens epithelial cells apoptosis and the targeting therapy toward posterior capsule opacification."
12/01/1998 - "To assess the safety and effectiveness of an immunotoxin, MDX-RA, designed to inhibit posterior capsule opacification (PCO). "
12/01/1998 - "Inhibition of posterior capsule opacification with an immunotoxin specific for lens epithelial cells: 24 month clinical results."
09/01/1994 - "By preventing the proliferation of human lens epithelial cells, immunotoxin 454A12-rRA may be useful in the management of posterior capsule opacification after planned extracapsular cataract surgery."
|1.||Intraocular Lenses (Intraocular Lens)
01/01/2004 - "The sharp-edge foldable intraocular lenses types (AcrySof MA3OBA, AcrySof SA3OAL, CeeOn 911A) showed statistically significant difference in posterior capsule opacification values in one-year follow-up time. "
11/01/2011 - "To assess the axial stability and posterior capsule opacification (PCO)-inhibiting efficacy of a microincision hydrophilic intraocular lens (IOL) (Idea 613 XC) and a standard hydrophobic open-loop acrylic IOL (Acrysof SA60AT). "
12/01/2013 - "Posterior capsule opacification with the iMics1 NY-60 and AcrySof SN60WF 1-piece hydrophobic acrylic intraocular lenses: 3-year results of a randomized trial."
08/01/2013 - "Posterior capsule opacification with the iMics1 NY-60 and AcrySof SN60WF 1-piece hydrophobic acrylic intraocular lenses: 3-year results of a randomized trial."
03/01/2012 - "Effect of intraocular lens asphericity on posterior capsule opacification between two intraocular lenses with same acrylic material: a fellow-eye study."
03/01/2001 - "Eradication of posterior capsule opacification: documentation of a marked decrease in Nd:YAG laser posterior capsulotomy rates noted in an analysis of 5416 pseudophakic human eyes obtained postmortem."
05/01/2015 - "This prospective clinical study included 97 patients having Nd:YAG laser posterior capsulotomy for posterior capsule opacification. "
01/01/2000 - "The study consisted of 3 parts: First, to evaluate posterior capsule opacification (PCO); the Nd:YAG laser posterior capsulotomy rate (%) was documented and plotted on a monthly basis, creating a computerized trend line for each IOL style. "
01/01/1998 - "While the incidence and treatment of posterior capsule opacification requires further study, the development of a low-cost YAG laser may be a solution. "
07/01/2015 - "We retrospectively evaluated 85 eyes of 67 patients treated with Nd:YAG laser posterior capsulotomy for posterior capsule opacification (PCO). "
01/01/2014 - "People with accommodative lenses were more likely to be spectacle-independent but the estimate was very uncertain (risk ratio (RR) 8.18; 95% CI 0.47 to 142.62, 1 study, 40 people, very low quality evidence).More cases of posterior capsule opacification (PCO) were seen in accommodative lenses but the effect of the lenses on PCO was uncertain (Peto odds ratio (OR) 2.12; 95% CI 0.45 to 10.02, 91 people, 2 studies, low quality evidence). "
01/01/2009 - "Inclusion CriteriaExclusion Criteriaadult patients with age-related cataractssystematic reviews, randomized controlled trials (RCTs) distance visual acuity (best corrected distance visual acuity), near visual acuity (best distance corrected near visual acuity) contrast sensitivity, depth of field, glare, quality of life, visual function, spectacle dependence, posterior capsule opacification.studies with fewer than 20 eyesIOLs for non-age related cataractsIOLs for presbyopiastudies with a mean follow-up <6monthsstudies reporting insufficient data for analysis COMPARISONS OF INTEREST: The primary comparison of interest was accommodative vs. multifocal vs. monofocal lenses. "
01/01/1988 - "[Experimental study of posterior capsule opacification and optic decentering of various posterior chamber lenses following intercapsular implantation]."
01/01/2008 - "The effect of hydrophobic acrylic foldable lenses on preventing anterior and posterior capsule opacification is mainly a result of the acrylic hydrophobic biomaterial."
05/01/2004 - "Posterior capsule opacification after implantation of CeeOn Edge 911A, PhacoFlex SI-40NB, and AcrySof MA60BM lenses: one-year results of an intraindividual comparison multicenter study."
10/01/2011 - "The impact of capsulorhexis diameter, localization and shape on posterior capsule opacification."
01/01/2008 - "Visual acuity, anterior capsule opacification (ACO), capsulorrhexis/optic overlapping, and posterior capsule opacification (PCO) were evaluated. "
05/01/2007 - "Visual acuity, anterior capsule opacification (ACO), capsular folds, capsulorrhexis/optic overlapping and posterior capsule opacification (PCO) were evaluated. "
10/01/2006 - "The area of capsulorhexis aperture was determined with computer software, and capsule opacification was graded subjectively. "
10/01/2006 - "The postoperative changes in capsulorhexis apertures and anterior capsule opacification (ACO) between Group A (aspiration of LECs) and Group B (control) were compared. "
|5.||Intraocular Lens Implantation
12/01/2014 - "Influence of intraocular lens implantation on anterior capsule contraction and posterior capsule opacification."
02/01/2012 - "Incidence and influence of posterior capsule striae on the development of posterior capsule opacification after 1-piece hydrophobic acrylic intraocular lens implantation."
12/01/2008 - "The pars plana lensectomy with double-capsule-supported intraocular lens implantation technique seems to be a safe and easy method in children, limiting postoperative IOL-related complications and posterior capsule opacification in the long term."
10/01/2004 - "Limitation of Scheimpflug videophotography system in quantifying posterior capsule opacification after intraocular lens implantation."
09/01/2004 - "The effects of three-piece or single-piece acrylic intraocular lens implantation on posterior capsule opacification."