Loose Anagen Hair Syndrome

Benign childhood alopecia that improves spontaneously with aging. It is characterized by anagen hairs (misshapen hair bulbs and absent inner and outer root sheaths), thin, and sparse hairs that pulls out easily.

Also Known As:

Networked: 11 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Alopecia Areata
2.	Alopecia (Baldness)
3.	Tinea Capitis
4.	Lichen Planus (Lichen Ruber Planus)
5.	Monilethrix

Experts

1.	Randolph, Michael: 1 article (03/2021)
2.	Tosti, Antonella: 1 article (03/2021)
3.	Flanigan, Kendall: 1 article (02/2021)
4.	Greer, Jeremy: 1 article (02/2021)
5.	Maruthur, Mario: 1 article (02/2021)
6.	Bhoyrul, B: 1 article (01/2021)
7.	Jerjen, R: 1 article (01/2021)
8.	Koh, W-L: 1 article (01/2021)
9.	Sinclair, R: 1 article (01/2021)
10.	Anouar, Ilyass: 1 article (03/2019)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Loose Anagen Hair Syndrome:

1.	Minoxidil (Rogaine)FDA LinkGeneric 01/01/2021 - "Low-dose oral minoxidil improves global hair density and length in children with loose anagen hair syndrome." 03/01/2019 - "Loose Anagen Syndrome: A Little Response to Minoxidil." 11/01/2018 - "Loose anagen hair syndrome: Treatment with systemic minoxidil characterised by marked hair colour change." 05/01/2014 - "A 2-year-old girl with a diagnosis of loose anagen hair syndrome was treated with a tapering regime of minoxidil 5% solution over 28 months, resulting in quick, significant clinical improvement with no adverse effects. " 05/01/2014 - "Minoxidil 5% solution for topical treatment of loose anagen hair syndrome."
2.	SolutionsIBA 05/01/2014 - "A 2-year-old girl with a diagnosis of loose anagen hair syndrome was treated with a tapering regime of minoxidil 5% solution over 28 months, resulting in quick, significant clinical improvement with no adverse effects. " 05/01/2014 - "Minoxidil 5% solution for topical treatment of loose anagen hair syndrome."
3.	Keratins (Keratin)IBA 04/01/2002 - "Another keratin, and possibly the type I partner of K6hf, could be responsible for loose anagen hair syndrome in other patients, or the gene involved may be a minor gene." 04/01/2002 - "Is the loose anagen hair syndrome a keratin disorder? " 10/01/2001 - "In addition, this keratin represents a new candidate gene for inherited structural hair defects such as loose anagen syndrome."
4.	Keratin-6 (Keratin 6A)IBA 02/15/2021 - "Loose anagen syndrome (LAS) is a hair disorder involving insufficient anchoring of the hair follicle to the scalp owing to an autosomal dominant or sporadic mutation in the gene encoding keratin 6. There are three phenotypes of LAS, including type B, which presents in young, light-haired girls as unruly, uncombable hair with diminished growth. "

Therapies and Procedures

1.	Traction 12/01/2014 - "The main noncicatricial alopecias are represented by androgenetic alopecia, alopecia areata, trichotillomania, traction and pressure alopecia, temporal triangular alopecia, ageing alopecia, loose anagen syndrome, telogen effluvium and anagen effluvium." 01/01/2012 - "Most of the cases present initially to dermatologists with complaints of loss of hair and is often confused with other dermatological conditions like alopecia areata, tinea capitis, traction alopecia, and loose anagen syndrome. " 06/01/2016 - "The differential diagnosis includes alopecia areata (Table 1) (6), tinea capitis, telogen effluvium, secondary syphilis, traction alopecia, loose anagen syndrome, lichen planopilaris, alopecia mucinosa, and scleroderma (2-5). "
2.	Drug Therapy (Chemotherapy) 03/01/2021 - "Androgenetic alopecia was the most studied condition, but other conditions included telogen effluvium, lichen planopilaris, loose anagen hair syndrome, monilethrix, alopecia areata, and permanent chemotherapy-induced alopecia. "