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Prehypertension

Blood pressure levels that are between normotension and hypertension. Individuals with prehypertension are at a higher risk for developing cardiovascular diseases. Generally, prehypertension is defined as SYSTOLIC PRESSURE of 131-139 mm Hg and/or DIASTOLIC PRESSURE of 81-89 when the optimal is 120/80 mm Hg. For diabetics and other metabolism diseases the prehypertension is around 110-129/70-79 mm Hg.
Also Known As:
Pre Hypertension; Pre-Hypertensions; Prehypertensions; Pre-Hypertension
Networked: 729 relevant articles (21 outcomes, 158 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hypertension (High Blood Pressure)
2. Masked Hypertension
3. Kidney Diseases (Kidney Disease)
4. Weight Loss (Weight Reduction)
5. Prediabetic State (Prediabetes)

Experts

1. Appel, Lawrence J: 9 articles (01/2018 - 09/2007)
2. Egan, Brent M: 8 articles (05/2015 - 10/2004)
3. Chang, Chih-Jen: 7 articles (01/2019 - 05/2008)
4. Lu, Feng-Hwa: 7 articles (01/2019 - 05/2008)
5. Wu, Jin-Shang: 7 articles (01/2019 - 05/2008)
6. Yang, Yi-Ching: 7 articles (01/2019 - 05/2008)
7. Zhang, Yonghong: 7 articles (09/2017 - 10/2008)
8. Azizi, Fereidoun: 6 articles (02/2022 - 08/2014)
9. Sun, Yingxian: 6 articles (01/2021 - 01/2010)
10. Zheng, Liqiang: 6 articles (01/2021 - 01/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Prehypertension:
1. Antihypertensive Agents (Antihypertensives)IBA
2. 4- (2- (4- hydroxybenzyl)- phenoxy)- N- methylbutylamineIBA
07/01/2008 - "If the results are equivocal, ambulatory BP monitoring may help to establish the diagnosis; (5) In patients with prehypertension, HBPM may be useful for detecting masked hypertension; (6) HBPM is recommended for evaluating the response to any type of antihypertensive treatment and may improve adherence; (7) The target HBPM goal for treatment is <135/85 mm Hg or <130/80 mm Hg in high-risk patients; (8) HBPM is useful in the elderly, in whom both BP variability and the white-coat effect are increased; (9) HBPM is of value in patients with diabetes, in whom tight BP control is of paramount importance; (10) Other populations in whom HBPM may be beneficial include pregnant women, children, and patients with kidney disease; and (11) HBPM has the potential to improve the quality of care while reducing costs and should be reimbursed."
07/01/2008 - "If the results are equivocal, ambulatory BP monitoring may help to establish the diagnosis; (5) In patients with prehypertension, HBPM may be useful for detecting masked hypertension; (6) HBPM is recommended for evaluating the response to any type of antihypertensive treatment and may improve adherence; (7) The target HBPM goal for treatment is <135/85 mm Hg or <130/80 mm Hg in high-risk patients; (8) HBPM is useful in the elderly, in whom both BP variability and the white-coat effect are increased; (9) HBPM is of value in patients with diabetes, in whom tight BP control is of paramount importance; (10) Other populations in whom HBPM may be beneficial include pregnant women, children, and patients with kidney disease; and (11) HBPM has the potential to improve the quality of care while reducing costs and should be reimbursed."
07/01/2008 - "If the results are equivocal, ambulatory BP monitoring may help to establish the diagnosis; (5) In patients with prehypertension, HBPM may be useful for detecting masked hypertension; (6) HBPM is recommended for evaluating the response to any type of antihypertensive treatment and may improve adherence; (7) The target HBPM goal for treatment is <135/85 mm Hg or <130/80 mm Hg in high-risk patients; (8) HBPM is useful in the elderly, in whom both BP variability and the white-coat effect are increased; (9) HBPM is of value in patients with diabetes, in whom tight BP control is of paramount importance; (10) Other populations in whom HBPM may be beneficial include pregnant women, children, and patients with kidney disease; and (11) HBPM has the potential to improve the quality of care while reducing costs and should be reimbursed."
06/01/2008 - "If the results are equivocal, ambulatory BP monitoring may help to establish the diagnosis; (5) In patients with prehypertension, HBPM may be useful for detecting masked hypertension; (6) HBPM is recommended for evaluating the response to any type of antihypertensive treatment and may improve adherence; (7) The target HBPM goal for treatment is <135/85 mm Hg or <130/80 mm Hg in high-risk patients; (8) HBPM is useful in the elderly, in whom both BP variability and the white-coat effect are increased; (9) HBPM is of value in patients with diabetes, in whom tight BP control is of paramount importance; (10) Other populations in whom HBPM may be beneficial include pregnant women, children, and patients with kidney disease; and (11) HBPM has the potential to improve the quality of care while reducing costs and should be reimbursed."
05/01/2008 - "If the results are equivocal, ambulatory BP monitoring may help to establish the diagnosis; 5) In patients with prehypertension, HBPM may be useful for detecting masked hypertension; 6) HBPM is recommended for evaluating the response to any type of antihypertensive treatment and may improve adherence; 7) The target HBPM goal for treatment is <135/85 mm Hg or <130/80 mm Hg in high-risk patients; 8) HBPM is useful in the elderly, in whom both BP variability and the white-coat effect are increased; 9) HBPM is of value in patients with diabetes, in whom tight BP control is of paramount importance; 10) Other populations in whom HBPM may be beneficial include pregnant women, children, and patients with kidney disease; and 11) HBPM has the potential to improve the quality of care while reducing costs and should be reimbursed."
3. Glucose (Dextrose)FDA LinkGeneric
4. LipidsIBA
5. CholesterolIBA
6. PolyphenolsIBA
7. CreatinineIBA
01/01/2019 - "Further adjustments for changes in body mass index, metabolic variables, and creatinine during the follow-up did not modify the strength of association between prehypertension and new-onset LVH. "
10/01/2013 - "(1) The morbidity of prehypertension as well as hypertension was 30.0% in coastal population of Fujian Province, there were more than 3 cardiovascular risk factors in 65.5% (909/1388) of the hypertensive population and 37.5% of the prehypertensive population.(2) The abnormal rates of creatinine ratio(UACR), baPWV, and CRAE in hypertensive [25.7% (357/1388) , 84.2% (1169/1388) , 29.5% (409/1388) ] and prehypertensive population [20.0% (176/880) , 29.1% (256/880) , 25.6% (225/880)] were significantly higher than those of normotensive individuals [8.5% (91/1076), 8.9% (96/1076), 18.8% (202/1076), all P < 0.05].(3) Prehypertension and hypertension served as independent risk factors of UACR, baPWV and CRAE according to logistic regression analysis. "
01/01/2019 - "Simple renal cysts are associated with prehypertension, hypertension, diabetes, and increased serum creatinine, which are risk factors of cardiovascular events. "
10/01/2013 - "Participants with a baPWV of 1,400 cm/s or greater (n = 1,028) had lower estimated glomerular filtration rates (eGFRs) but higher serum creatinine levels and greater prevalences of mild and moderate CKD, diabetes mellitus, prediabetes mellitus, hypertension, and prehypertension than those with baPWV less than 1,400 cm/s (n = 223). "
04/01/2012 - "This study was operated to investigate the association between urinary albumin-to-creatinine ratio (ACR) and prehypertension among Chinese Han women. "
8. Vitamin DFDA LinkGeneric
9. Amlodipine (Norvasc)FDA LinkGeneric
10. Losartan (Cozaar)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Dietary Approaches To Stop Hypertension
3. Psychology Biofeedback (Biofeedback)
4. Home Nursing (Nursing, Home)
5. Massage (Zone Therapy)