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Islet Amyloid Polypeptide

A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS.
Also Known As:
Amlintide; Amylin; IAPP Precursor; IAPP Protein; Insulinoma Amyloid Polypeptide; Insulinoma Amyloid Polypeptide Precursor; Islet Amyloid Polypeptide Precursor; Pancreatic Amylin; Amylin, Pancreatic; Amyloid Polypeptide, Insulinoma; Amyloid Polypeptide, Islet; Polypeptide, Insulinoma Amyloid; Polypeptide, Islet Amyloid
Networked: 1568 relevant articles (41 outcomes, 162 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Raleigh, Daniel P: 39 articles (11/2020 - 02/2002)
2. Lutz, Thomas A: 38 articles (04/2022 - 03/2005)
3. Butler, Peter C: 28 articles (01/2022 - 07/2003)
4. Verchere, C Bruce: 21 articles (01/2020 - 02/2003)
5. Gurlo, Tatyana: 19 articles (01/2022 - 06/2004)
6. Roth, Jonathan D: 18 articles (07/2015 - 12/2006)
7. Despa, Florin: 17 articles (01/2021 - 02/2012)
8. Ding, Feng: 16 articles (01/2022 - 01/2016)
9. Kahn, Steven E: 16 articles (11/2020 - 02/2002)
10. Hull, Rebecca L: 15 articles (11/2020 - 02/2003)

Related Diseases

1. Type 2 Diabetes Mellitus (MODY)
2. Body Weight (Weight, Body)
3. Obesity
4. Alzheimer Disease (Alzheimer's Disease)
5. Amyloidosis

Related Drugs and Biologics

1. pramlintide (Symlin)
2. Insulin (Novolin)
3. Leptin
4. Amyloid (Amyloid Fibrils)
5. Glucose (Dextrose)
6. Calcitonin Receptors (Calcitonin Receptor)
7. Peptides (Polypeptides)
8. Hormones (Hormone)
9. Glucagon-Like Peptide 1 (GLP 1)
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Therapeutics
2. Bariatric Surgery
3. Islets of Langerhans Transplantation
4. Drug Therapy (Chemotherapy)
5. Glycemic Control