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Triploidy

Polyploidy with three sets of chromosomes. Triploidy in humans are 69XXX, 69XXY, and 69XYY. It is associated with HOLOPROSENCEPHALY; ABNORMALITIES, MULTIPLE; PARTIAL HYDATIDIFORM MOLE; and MISCARRAGES.
Also Known As:
Triploid; Triploidies; Triploids
Networked: 812 relevant articles (9 outcomes, 53 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Triploidy
2. Trisomy (Trisomies)
3. Down Syndrome (Down's Syndrome)
4. Weight Gain
5. Tetraploidy

Experts

1. Liu, Yun: 16 articles (12/2015 - 11/2004)
2. Liu, Shaojun: 13 articles (12/2015 - 03/2006)
3. Nicolaides, Kypros H: 9 articles (01/2014 - 02/2007)
4. Zhang, Chun: 8 articles (04/2015 - 10/2006)
5. Nicolaides, K H: 8 articles (06/2013 - 06/2000)
6. Tao, Min: 7 articles (12/2015 - 06/2007)
7. Zhou, Yi: 6 articles (12/2015 - 09/2012)
8. Zhong, Huan: 5 articles (12/2015 - 10/2009)
9. Arai, Katsutoshi: 5 articles (11/2015 - 05/2002)
10. Xiao, Jun: 5 articles (04/2015 - 06/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Triploidy:
1. Patau syndromeIBA
2. Biological Markers (Surrogate Marker)IBA
3. alpha-Fetoproteins (AFP)IBA
4. Dihydrotachysterol (AT 10)IBA
5. Testosterone (Sustanon)FDA Link
09/01/2001 - "Diploid females showed levels of testosterone and estradiol-17beta significantly higher than those of triploids (P < 0.05), in which no endocrine signs of maturation were observed at all. "
05/10/2010 - "We evaluated plasma testosterone (T) and 17beta-estradiol (E2) levels and ovarian aromatase CYP19a gene expression following a single intraperitoneal injection of Chilean pulp and paper mill effluent extracts into juvenile triploid rainbow trout. "
03/01/2003 - "Compared to triploids fed a normal diet (i.e., control-triploids), the administration of 30 mg E(2)/kg feed to triploids (i.e., E(2)-treated-triploids) led to the development of secondary sex characteristics, a significant reduction in hematocrit and total blood hemoglobin level, a decrease in plasma testosterone and no weight gain. "
02/01/2013 - "In this study, the annual cycle of the gonadal steroids testosterone (T), 11-ketotestosterone (11-KT), 17β-estradiol (E2) and 17α, 20β-dihydroxy-4-pregnen-3-one (DHP) was determined using radioimmunoassay and then compared for two populations of rainbow trout, XX diploid females (n = 40) and XXX triploid females (n = 15). "
05/01/2010 - "After 13 months, amounts of gonadotropic hormone (GtH-I, GtH-II) and oestradiol (17beta-E(2)) in triploid females were lower than in diploid fish at corresponding time periods, but the amounts of testosterone (T) increased consistently after 21 months and were more than in diploid fish in the corresponding time periods (P > 0.05). "
6. Insulin-Like Growth Factor I (IGF-1)IBA
7. Hemoglobins (Hemoglobin)IBA
8. Dacarbazine (DIC)FDA LinkGeneric
9. Insulin-Like Growth Factor Binding ProteinsIBA
10. Transforming Growth Factor beta (TGF-beta)IBA

Therapies and Procedures

1. Transplants (Transplant)
2. Transplantation (Transplant Recipients)
3. Induced Abortion (Induced Abortions)
4. Homologous Transplantation (Allograft)
5. Heterologous Transplantation (Xenotransplantation)