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Cystine-Knot Miniproteins

A structurally-related family of small proteins that form a stable tertiary fold pattern which is supported by a series of disulfide bonds. The arrangement of disulfide bonds between the CYSTEINE moieties results in a knotted structure which is unique to this family of proteins.
Also Known As:
Knottin; Knottins; Cystine Knot Miniproteins
Networked: 16 relevant articles (0 outcomes, 5 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Cochran, Jennifer R: 13 articles (01/2015 - 03/2009)
2. Kimura, Richard H: 11 articles (06/2015 - 03/2009)
3. Cheng, Zhen: 9 articles (06/2015 - 03/2009)
4. Miao, Zheng: 6 articles (11/2014 - 12/2009)
5. Jiang, Lei: 5 articles (06/2015 - 12/2009)
6. Gambhir, Sanjiv Sam: 4 articles (06/2015 - 03/2009)
7. Liu, Hongguang: 3 articles (04/2011 - 12/2009)
8. Gambhir, Sanjiv S: 3 articles (11/2010 - 03/2010)
9. Tu, Yingfeng: 2 articles (06/2015 - 11/2014)
10. Shi, Hongcheng: 2 articles (06/2015 - 11/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Glioblastoma (Glioblastoma Multiforme)
3. Atherosclerotic Plaque (Atheroma)
4. Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
5. Pain (Aches)

Related Drugs and Biologics

1. Spider Venoms (Venom, Spider)
2. CY5.5 cyanine dye
3. Peptides
4. Cystine-Knot Miniproteins
5. Integrins
6. Vitronectin
7. Trypsin
8. Cystine (L-Cystine)
9. Ion Channels (Ion Channel)
10. Fibronectins (Fibronectin)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Microbubbles
3. Therapeutics