|1.||Dou, Q Ping: 15 articles (01/2015 - 09/2003)|
|2.||Figueiredo-Pereira, Maria E: 9 articles (10/2012 - 07/2002)|
|3.||Wang, Xuejun: 6 articles (11/2015 - 11/2005)|
|4.||Liu, Jinbao: 5 articles (11/2015 - 02/2006)|
|5.||Chen, Di: 5 articles (07/2009 - 11/2006)|
|6.||Cui, Qiuzhi Cindy: 4 articles (01/2011 - 11/2006)|
|7.||Jansen, Marlon: 4 articles (01/2011 - 07/2002)|
|8.||Yang, Huanjie: 4 articles (05/2009 - 11/2006)|
|9.||Landis-Piwowar, Kristin R: 4 articles (09/2008 - 11/2006)|
|10.||Li, Zongmin: 4 articles (07/2004 - 07/2002)|
08/01/2011 - "To identify ubiquitinated proteins from complex human multiple myeloma (MM) U266 cells, a malignant disorder of differentiated human B cells. "
08/01/2011 - "Identification of ubiquitinated proteins from human multiple myeloma U266 cells by proteomics."
08/19/2003 - "Novel agents that target the proteasome, a proteolytic complex responsible for the degradation of ubiquitinated proteins, have demonstrated remarkable therapeutic efficacy in multiple myeloma, a plasma cell malignancy. "
06/01/2014 - "Inhibition of proteasome, a proteolytic complex responsible for the degradation of ubiquitinated proteins, has emerged as a powerful strategy for treatment of multiple myeloma (MM), a plasma cell malignancy. "
12/01/2014 - "AS-06 and AS-29 significantly suppress the degradation of the proteasome-sensitive fluorescent proteins in HEK293PS cells, and induce the accumulation of ubiquitinated proteins in human multiple myeloma cells. "
01/01/2015 - "In this study, we sought to detect whether ubiquitinated proteins enriched from tumor cells could be used directly as a novel cancer vaccine. "
11/09/2015 - "Treatment of tumor cells with CB-5083 leads to accumulation of poly-ubiquitinated proteins, retention of endoplasmic reticulum-associated degradation (ERAD) substrates, and generation of irresolvable proteotoxic stress, leading to activation of the apoptotic arm of the unfolded protein response. "
12/15/2013 - "Accumulation of ubiquitinated proteins, and increased p27 as well as decreased NF-κB expression were detected in tumor tissues of DDTC-Cu(I)-treated group. "
05/16/2014 - "However, possible regulation of the proteasome's capacity to degrade ubiquitinated proteins has received little attention, although proteasome inhibitors are widely used in research and cancer treatment. "
11/01/2006 - "In addition, when administered to mice bearing MDA-MB-231 tumor xenografts, DSF significantly inhibited the tumor growth (by 74%), associated with in vivo proteasome inhibition (as measured by decreased levels of tumor tissue proteasome activity and accumulation of ubiquitinated proteins and natural proteasome substrates p27 and Bax) and apoptosis induction (as shown by caspase activation and apoptotic nuclei formation). "
08/01/2012 - "Our histopathological and in vitro studies suggest that accumulation of ubiquitinated proteins in neuronal cells might be associated with neuronal apoptosis caused by WNV infection."
02/05/2013 - "Baculovirus AcMNPV causes proteotoxicity in Sf9 cells as revealed by accumulation of ubiquitinated proteins and aggresomes in the course of infection. "
01/01/2013 - "pylori infection increased the interaction between Akt and VCP, Akt-dependent phosphorylation of VCP, levels of ubiquitinated proteins, and aggresome formation in AGS cells. "
08/01/2012 - "In addition, accumulation of ubiquitinated proteins was markedly enhanced in mouse neuroblastoma, Neuro-2a cells after WNV infection. "
07/01/2013 - "We show that levels of ubiquitinated proteins are reduced during PEDV infection and that PEDV PLP2 has deubiquitinase (DUB) activity that recognizes and processes both K-48 and K-63 linked polyubiquitin chains. "
|4.||Transient Ischemic Attack
01/01/2015 - "Our previous studies have demonstrated that autophagosome-enriched vaccine (named DRibbles: DRiPs-containing blebs) induce a potent anti-tumor efficacy in different murine tumor models, in which DRibble-containing ubiquitinated proteins are efficient tumor-specific antigen source for the cross-presentation after being loaded onto dendritic cells. "
|1.||Proteasome Endopeptidase Complex (Proteasome)
|2.||Proteins (Proteins, Gene)
|7.||ATP dependent 26S protease (26S proteasome)
|8.||NF-kappaB inhibitor alpha
|10.||I-kappa B Proteins (I kappa B)
|1.||Heterologous Transplantation (Xenotransplantation)