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DAX-1 Orphan Nuclear Receptor

An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.
Also Known As:
DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein; Nuclear Receptor 0B1; Nuclear Receptor DAX-1; Nuclear Receptor NR0B1; Nuclear Receptor Subfamily 0, Group B, Member 1; DAX 1 Orphan Nuclear Receptor; DSS AHC Critical Region on the X Chromosome, Gene 1 Protein; Nuclear Receptor DAX 1
Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Castells, Salvador: 1 article (01/2015)
2. Perez-Colon, Sheila: 1 article (01/2015)
3. Bansal, Shipra: 1 article (01/2015)
4. Umpaichitra, Vatcharapan: 1 article (01/2015)
5. Sirianni, R: 1 article (01/2013)
6. Sisci, D: 1 article (01/2013)
7. Lanzino, M: 1 article (01/2013)
8. Morelli, C: 1 article (01/2013)
9. Barone, I: 1 article (01/2013)
10. Catalano, S: 1 article (01/2013)

Related Diseases

1. Breast Neoplasms (Breast Cancer)
2. Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
3. Pituitary Neoplasms (Pituitary Adenoma)
4. Hypogonadism (Hypergonadotropic Hypogonadism)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Androgen Receptors (Androgen Receptor)
2. X-linked adrenal hypoplasia congenita
3. Dosage-sensitive sex reversal
4. Hormones
5. Estrogens (Estrogen)
6. Aromatase (CYP19)
7. familial Hypoadrenocorticism
8. Hyperglycerolemia