|1.||Zhu, Yong: 4 articles (05/2015 - 04/2009)|
|2.||Hoffman, Aaron E: 4 articles (05/2015 - 04/2009)|
|3.||Sancar, Aziz: 4 articles (06/2011 - 07/2002)|
|4.||Doi, Masao: 3 articles (03/2014 - 02/2010)|
|5.||Zheng, Tongzhang: 3 articles (04/2010 - 04/2009)|
|6.||Stevens, Richard G: 3 articles (04/2010 - 04/2009)|
|7.||Ba, Yue: 3 articles (04/2010 - 04/2009)|
|8.||Leaderer, Derek: 3 articles (04/2010 - 04/2009)|
|9.||Størmer, Fredrik C: 2 articles (04/2015 - 09/2012)|
|10.||Okamura, Hitoshi: 2 articles (03/2014 - 02/2010)|
06/01/2015 - "Cryptochrome 2 (CRY2) is a circadian clock protein involved in cell cycle, but the biologic consequences of this activity in cancer are poorly understood. "
01/01/2014 - "Mice with mutations in Cryptochrome 1 and 2 are arrhythmic (lack a circadian rhythm) and arrhythmic mice have a faster rate of growth of implanted tumors. "
09/01/2010 - "Links between the circadian clock genes Periods, Bmal1, and Cryptochromes and aging and cancer are emerging. "
01/01/2010 - "Phenotypic effects of the circadian gene Cryptochrome 2 on cancer-related pathways."
02/24/2009 - "However, it was found that disruption of the clock by the Cryptochrome (Cry) mutation in mice did not increase cancer rate in the mutant mice even after exposing the animals to ionizing radiation. "
06/01/2014 - "Evidence for the role of cryptochromes, core components of the system, in regulating glucose homeostasis is not supported by CRY1 candidate gene association studies for diabetes and insulin resistance in human, suggesting possible dietary influences. "
07/01/2013 - "Although the levels of Bmal1 (brain and muscle Arnt-like protein-1), Per2 (period 2), and Cry1 (cryptochrome 1) mRNA expression in the liver change during the progress of insulin resistance conditions, the gene expression patterns still show circadian rhythmicity. "
|3.||Non-Hodgkin Lymphoma (Lymphosarcoma)
|4.||Photophobia (Light Sensitivity)
11/01/2014 - "Cellular metabolites enhance the light sensitivity of Arabidopsis cryptochrome through alternate electron transfer pathways."
04/09/2013 - "Drosophila CRYPTOCHROME (dCRY) is involved in light synchronization of the master circadian clock, and its C terminus plays an important role in modulating light sensitivity and activity of the protein. "
01/01/2013 - "Drosophila melanogaster shows exquisite light sensitivity for modulation of circadian functions in vivo, yet the activities of the Drosophila circadian photopigment cryptochrome (CRY) have only been observed at high light levels. "
01/01/2013 - "Exquisite light sensitivity of Drosophila melanogaster cryptochrome."
03/03/1998 - "Enhancement of blue-light sensitivity of Arabidopsis seedlings by a blue light receptor cryptochrome 2."
|5.||Breast Neoplasms (Breast Cancer)
11/13/2015 - "A synthetic cryptochrome inhibitor induces anti-proliferative effects and increases chemosensitivity in human breast cancer cells."
05/01/2015 - "Although the role of core circadian gene cryptochrome 2 (CRY2) in breast tumorigenesis has been demonstrated, the correlations of CRY2 with clinical parameters in breast cancer patients and its involvement in epigenetic processes such as DNA methylation remain relatively unexplored. "
01/01/2013 - "Considerable expression of key circadian genes, PERIOD 2, CLOCK, TIMELESS, CRYPTOCHROME 1, and CRYPTOCHROME 2 was also seen in all breast cancer cell lines and all patients' breast cancer tissues. "
06/01/2011 - "Disruption of the circadian rhythm or biological clock, which is regulated by a number of clock genes, including circadian locomotor output cycles kaput (CLOCK), period genes (PERs), and cryptochrome genes (CRYs), is a risk factor for breast cancer. "
11/13/2015 - "Cryptochrome (CRY), a circadian transcription factor, is a risk factor for initiation of breast cancer, and it is differentially expressed between normal and breast cancer tissues. "
|3.||Ferrosoferric Oxide (Magnetite)
|4.||Rhodopsin (Visual Purple)
|5.||Proteins (Proteins, Gene)
|7.||Member 2 Group A Nuclear Receptor Subfamily 4
|9.||mu Opioid Receptors (mu Opioid Receptor)
|10.||Reactive Oxygen Species (Oxygen Radicals)
|1.||Drug Therapy (Chemotherapy)