|1.||Vahteristo, Pia: 5 articles (10/2014 - 10/2011)|
|2.||Aaltonen, Lauri A: 4 articles (10/2014 - 10/2011)|
|3.||Sjöberg, Jari: 4 articles (10/2014 - 10/2011)|
|4.||Mäkinen, Netta: 4 articles (10/2014 - 10/2011)|
|5.||Kämpjärvi, Kati: 3 articles (10/2014 - 11/2013)|
|6.||Bützow, Ralf: 3 articles (09/2014 - 11/2013)|
|7.||Xu, Wei: 2 articles (10/2015 - 01/2015)|
|8.||Boyer, Thomas G: 2 articles (10/2015 - 09/2014)|
|9.||Surti, Urvashi: 2 articles (08/2015 - 01/2012)|
|10.||Rajkovic, Aleksandar: 2 articles (08/2015 - 01/2012)|
09/01/2015 - "In contrast, Eqn exposure upregulated several cancer-related genes, such as mediator complex subunit 16 and RAS oncogene family members, suggesting a carcinogenic potential for Eqn. "
12/01/2013 - "Mediator complex (MED) is an essential multi-subunit component of the transcription apparatus and plays a key role in the transcription regulation of many genes involved in several diseases, including cancer. "
05/01/2013 - "Using ERM as a prototype, we show that the minimal N-terminal TAD activates transcription by contacting the activator interacting domain (ACID)/Prostate tumor overexpressed protein 1 (PTOV) domain of the Mediator complex subunit MED25. "
11/21/2012 - "We used a large-scale RNAi screen to identify MED12, a component of the transcriptional MEDIATOR complex that is mutated in cancers, as a determinant of response to ALK and EGFR inhibitors. "
11/01/2012 - "The goal of this study was to investigate the effect of the gene silencing of mediator complex subunit 19 (MED19) on cell viability and tumor growth in ovarian cancer. "
|2.||Leiomyoma (Uterine Fibroids)
04/01/2015 - "Although somatic mutations in exon 2 of the mediator complex subunit 12 (MED12) gene have been reported previously in uterine fibroids in women from Finland, South Africa, and North America, the status of these mutations was not reported in the Southern United States women. "
03/01/2015 - "Somatic mutations in mediator complex subunit 12 (MED12) have emerged as a critical genetic change in the development of uterine leiomyomas. "
01/01/2015 - "Mutations in Mediator Complex Subunit 12 (MED12) gene are typical genomic aberrations, commonly detected in a high percentage of uterine leiomyomas (ULs). "
10/01/2014 - "To determine the frequency of mediator complex subunit 12 (MED12) mutations in well-documented, prospectively collected, unselected series of sporadic uterine leiomyomas to better understand the contribution of MED12 mutations in leiomyoma genesis. "
09/01/2014 - "We recently discovered by exome sequencing that specific exon 2 mutations in mediator complex subunit 12 (MED12) are extremely common in uterine leiomyomas. "
|3.||Pancreatic Neoplasms (Pancreatic Cancer)
12/01/2011 - "MED29, a component of the mediator complex, possesses both oncogenic and tumor suppressive characteristics in pancreatic cancer."
08/01/2011 - "This study reports on short hairpin RNA (shRNA)-mediated gene silencing of MED19, a subunit of Mediator complex, and its effect on the growth of pancreatic cancer cells. "
12/13/2005 - "After heat shock, there is a significant recruitment of the heat-shock transcription factor, RNA polymerase II, XPD, GCN5, TRRAP, or Mediator complex 13 to the hsp70 promoter. "
12/13/2005 - "These studies indicate that the hsp70 promoter is already occupied by TATA-binding protein (TBP) and several TBP-associated factors (TAFs), TFIIB, TFIIF (RAP30), TFIIH (XPB), TBP-free/TAF-containg complex (GCN5 and TRRAP), and the Mediator complex subunit 13 before heat shock. "
|5.||Ovarian Neoplasms (Ovarian Cancer)
|1.||Transcription Factor TFIIB (TFIIB)
|2.||TATA-Binding Protein Associated Factors (TBP-Associated Factor)
|3.||TATA-Box Binding Protein (TATA-Binding Protein)
|4.||Small Interfering RNA (siRNA)
|6.||transcription factor TFIIF (TFIIF)
|7.||tributyl phosphate (TBP)
|8.||RNA Polymerase II (RNA Polymerase B)
|9.||Transcription Factors (Transcription Factor)