|1.||Stress Urinary Incontinence
|5.||Wounds and Injuries (Trauma)
|1.||Bai, Sang Wook: 17 articles (02/2015 - 03/2002)|
|2.||Altman, Daniel: 12 articles (09/2012 - 01/2004)|
|3.||Barber, Matthew D: 11 articles (12/2015 - 05/2006)|
|4.||Zhu, Lan: 11 articles (10/2015 - 01/2002)|
|5.||Kim, Sei Kwang: 10 articles (02/2015 - 04/2002)|
|6.||Thakar, Ranee: 9 articles (09/2015 - 02/2006)|
|7.||Rogers, Rebecca G: 8 articles (12/2015 - 07/2004)|
|8.||Sultan, Abdul H: 8 articles (09/2015 - 02/2006)|
|9.||Paraiso, Marie Fidela R: 8 articles (05/2015 - 05/2004)|
|10.||Jeon, Myung Jae: 8 articles (02/2015 - 03/2009)|
01/01/2009 - "A retrospective study was carried out to evaluate which mesh (cadaveric fascia lata (Tutoplast or Prolene mesh) is associated with the best outcome of laparoscopic sacrocolpopexy for vaginal vault prolapse. "
01/01/2012 - "Trans-vaginal total pelvic floor repair using a customized prolene mesh is safe and effective treatment for comprehensive repair of high-grade pelvic organ prolapse. "
09/01/2013 - "Laparoscopic Y-shaped polypropylene mesh for treatment of uterine and vaginal vault prolapse is a safe and effective method, especially applicable to preserve the uterus, and higher requirements of sexual life of patients."
01/01/1999 - "Colposacropexy with Prolene mesh is a safe and effective technique for the surgical therapy of vaginal vault prolapse."
01/01/2012 - "Outcome and efficacy of a transobturator polypropylene mesh kit in the treatment of anterior pelvic organ prolapse."
|2.||Estrogens (Estrogen)FDA Link
01/01/2015 - "Vaginal estrogen application before pelvic organ prolapse surgery improved the vaginal maturation index and increased vaginal epithelial thickness. "
11/01/2013 - "The aim of the study was to identify the differential expression of estrogen-related genes that may be involved in the menopause and pelvic organ prolapse (POP) using microarray analysis. "
11/01/2013 - "Estrogen-related genome-based expression profiling study of uterosacral ligaments in women with pelvic organ prolapse."
09/01/2011 - "The aim of this study was to examine the association between fracture and pelvic organ prolapse (POP) in postmenopausal women enrolled in the Women's Health Initiative Estrogen Plus Progestin trial. "
01/01/2008 - "Association of pelvic organ prolapse and fractures in postmenopausal women: analysis of baseline data from the Women's Health Initiative Estrogen Plus Progestin trial."
06/01/2014 - "Recent studies of genetic dysfunction in pelvic organ prolapse: the role of collagen defects."
02/01/2012 - "The systematic analysis of the native structure and mechanical properties of collagen within a tissue provides a potential way to study non-fatal conditions such as pelvic organ prolapse and other genito-urinary disorders, where the initial symptoms are subtle and multivariate, and where early detection of patient's condition may allow better non-invasive interventions and reduce the number of women undergoing surgical correction of these common disorders."
02/01/2011 - "The main goal of this study was to evaluate the potential of collagen meshes derived from porcine dermis as scaffolds for repairing pelvic organ prolapses. "
04/01/2015 - "Collagen structure deterioration in the skin of patients with pelvic organ prolapse determined by atomic force microscopy."
02/01/2015 - "Homeobox (HOX) A11 is a key transcriptional factor that controls collagen metabolism and homoeostasis in the uterosacral ligaments (USLs), and the deficient HOXA11 signalling may contribute to alterations in the biochemical strength of the USLs, leading to pelvic organ prolapse (POP). "
|4.||Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA
06/01/2012 - "The purpose of this study was to investigate the expression of fibulin-5 and lysyl oxidase-like 1 (LOXL1), which play an essential role in the synthesis and assembly of elastic fibers, in the uterosacral ligaments of women with advanced pelvic organ prolapse (POP) compared with controls. "
07/01/2009 - "The purpose of this study was to investigate expression of fibulin-5 and lysyl oxidase-like 1, which play an essential role in synthesis and assembly of elastic fibers in the uterosacral ligament, in samples taken from women with advanced pelvic organ prolapse compared with controls. "
09/01/2014 - "Validation of genetically matched wild-type strain and lysyl oxidase-like 1 knockout mouse model of pelvic organ prolapse."
07/01/2010 - "Suppression of lysyl oxidase gene expression by methylation in pelvic organ prolapse."
07/01/2009 - "Changes in expression of fibulin-5 and lysyl oxidase-like 1 associated with pelvic organ prolapse."
|5.||Messenger RNA (mRNA)IBA
11/01/2005 - "Patients with severe pelvic organ prolapse (grade > or = 3) have a significant reduction in the mRNA expression of lysyl oxidase as compared to asymptomatic controls. "
03/01/2014 - "To compare the mRNA and protein expressions of mitochondrial fusion protein-2 (mitofusin-2, Mfn2), and procollagen 1A1/1A2/3A1 in uterosacral ligament fibroblasts of postmenopausal patients with or without pelvic organ prolapse (POP). "
05/01/2011 - "Expression of neutrophil elastase and matrix metalloproteinase-2 mRNA was higher in women with pelvic organ prolapse than in those without pelvic organ prolapse. "
11/01/2005 - "To determine the mRNA expression of lysyl oxidase (LOX) and transforming growth factor beta2 (TGF beta2) in subjects with advanced pelvic organ prolapse as compared to asymptomatic controls. "
10/01/2015 - "The results have shown that SMOOTH-mode erbium laser seems to be an effective and safe method for treating vaginal laxity, stress urinary incontinence, pelvic organ prolapses and vaginal atrophy. "
10/01/2015 - "This erbium laser technology is used for treatments of vaginal laxity, stress urinary incontinence, pelvic organ prolapse and vaginal atrophy. "
09/01/2015 - "We hypothesize that Fibrillin-1 gene expression is altered in pelvic organ prolapse. "
09/01/2015 - "Is There a Relationship Between Pelvic Organ Prolapse and Tissue Fibrillin-1 Levels?"
09/01/2015 - "The results did not indicate a significant reduction in Fibrillin-1 gene expression in pelvic prolapse disorders; however, reduced Fibrillin-1 may contribute to increased pelvic organ prolapse risk with age and menopause. "
|8.||Proteins (Proteins, Gene)IBA
06/01/2014 - "Expression of extracellular matrix-remodeling proteins is altered in vaginal tissue of premenopausal women with severe pelvic organ prolapse."
10/01/2012 - "Pelvic organ prolapse (POP) is associated with menopause and changes in the proteins of the pelvic supporting system, but there is scant data on the precise alterations in Malaysian women. "
04/01/2012 - "Tissue samples of USL from women with and without pelvic organ prolapse (POP) were subjected to immunohistochemistry against ERα, ERβ, PR, and LGR7 proteins. "
07/01/2009 - "Previously, we have shown that HOXA11 is necessary for the development of the USLs, is deficient in women with pelvic organ prolapse (POP) and regulates expression of extracellular matrix (ECM) proteins. "
10/01/2007 - "Candidate genes have been identified that may result in alteration of the normal metabolism of various structural proteins which may ultimately predispose some women to both urogenital prolapse and stress incontinence. "
|9.||Progesterone Receptors (Progesterone Receptor)IBA
01/01/2009 - "Progesterone receptor polymorphism is associated with pelvic organ prolapse risk."
10/31/2004 - "Recent studies have been reported the roles of the estrogen receptor (ER), progesterone receptor (PR) and p53 in the development of a pelvic organ prolapse (POP). "
08/01/2010 - "Hypertrophic cervical elongation was defined as the difference between point C and point D of the Pelvic Organ Prolapse Quantification system greater than 8 cm. Estrogen and progesterone receptor levels are greater in women with hypertrophic cervical elongation compared with a normal cervix."
01/01/2009 - "Progesterone and progesterone receptors (PGR) are known to play important roles in the pathophysiology of pelvic organ prolapse (POP). "
11/01/2005 - "Roles of estrogen receptor, progesterone receptor, p53 and p21 in pathogenesis of pelvic organ prolapse."
07/01/2011 - "A secondary analysis of a trial of 114 subjects who underwent surgery for anterior pelvic organ prolapse who were assigned randomly to standard anterior colporrhaphy, ultralateral colporrhaphy, or anterior colporrhaphy plus polyglactin 910 mesh from 1996-1999. "
07/01/2011 - "A randomised controlled trial evaluating the use of polyglactin (Vicryl) mesh, polydioxanone (PDS) or polyglactin (Vicryl) sutures for pelvic organ prolapse surgery: outcomes at 2 years."
05/01/2008 - "A randomised controlled trial evaluating the use of polyglactin mesh, polydioxanone and polyglactin sutures for pelvic organ prolapse surgery."
05/01/2008 - "To compare the effectiveness of polyglactin mesh, and polydioxanone or polyglactin sutures in women having pelvic organ prolapse surgery. "
07/01/2011 - "The effects at 2 years of polyglactin (Vicryl) mesh inlay and polydioxanone (PDS) or polyglactin (Vicryl) suture material on prolapse symptoms, urinary, bowel, sexual function and prolapse related Quality-of-Life (QoL) in women undergoing pelvic organ prolapse surgery were evaluated in a randomised controlled trial with a 2 × 2 factorial design of Vicryl mesh (n = 32) or not (n = 34) and PDS (n = 33) or Vicryl suture (n = 33). "
03/01/2001 - "The cube and Gellhorn pessaries were thought to be the most effective for vaginal vault prolapse. "
06/01/2011 - "Although there is evidence that the use of pessaries in the treatment of pelvic organ prolapse is effective in alleviating symptoms and that patient satisfaction is high, the follow-up in many published papers is short, and the use of validated urogynaecological questionnaires is limited. "
01/01/2011 - "Use of a pessary in treatment of pelvic organ prolapse is associated with good compliance, and results in significant improvement in quality of life and urinary and bowel symptoms. "
07/01/2000 - "Neonatal pelvic organ prolapse has also been treated successfully with pessaries. "
10/01/2011 - "Vaginal pessaries are safe, simple and effective treatment for pelvic organ prolapse. "
10/01/2014 - "The literature demonstrates the safety and efficacy of robotic-assisted laparoscopy for hysterectomy and pelvic organ prolapse repair; however, most level I data show increased operative time and cost. "
10/01/2010 - "SRALS is effective for repair of apical vaginal defects in patients with significant pelvic organ prolapse who have not undergone previous hysterectomy. "
12/01/2007 - "While attending to women presenting with pelvic floor relaxation and pelvic organ prolapse, both with intact uterus or after hysterectomy, urogynecologists are constantly looking for simple, safe and effective ways to cure this supportive pelvic floor defect. "
09/01/2004 - "We suggest, based on presented data, that suspension of vagina to sacrospinosus ligament can be effective and safe method of surgery for women with vaginal vault prolapse after hysterectomy."
07/01/2015 - "To evaluate efficacy of the Elevate Anterior and Apical (EAA) in the repair of pelvic organ prolapse (POP) when performed after previous hysterectomy and with or without uterine preservation during POP surgery. "
|3.||Suburethral Slings (Tension-Free Vaginal Tape)
01/01/2014 - "Pelvic organ prolapse surgery with and without tension-free vaginal tape in women with occult or asymptomatic urodynamic stress incontinence: a randomised controlled trial."
01/01/2006 - "The aim of this study is to evaluate the efficacy and feasibility of concomitant pelvic reconstructive surgery with tension-free vaginal tape (TVT) procedure to treat pelvic organ prolapse women with urodynamic stress incontinence (USI) or occult USI. "
10/01/2014 - "Outcomes of minimally invasive suburethral slings with and without concomitant pelvic organ prolapse surgery."
03/01/2014 - "The tension-free vaginal mesh plus transobturator tape procedure improves lower urinary tract symptoms in the majority of patients presenting pelvic organ prolapse."
01/01/2014 - "We set out to determine if insertion of a retropubic tension-free vaginal tape (TVT) sling at the time of pelvic organ prolapse surgery improves continence outcomes in women with pre-operative occult stress incontinence (OSI) or asymptomatic urodynamic stress incontinence (USI). "
09/01/2010 - "The aim was to assess the efficacy of three-compartment pelvic organ prolapse (POP) vaginal repair using the InteXen biocompatible porcine dermal graft as compared to traditional colporrhaphy with sacrospinous ligament suspension. "
03/01/2010 - "Our study demonstrates a significantly lower erosion rate when using a "commercial kit" to repair pelvic organ prolapse compared to our traditional synthetic graft-augmented repair."
12/01/2005 - "This study was undertaken to evaluate the outcomes of vaginal surgery for pelvic organ prolapse, comparing cases implementing graft augmentation to those without graft augmentation. "
11/01/2014 - "Transvaginal repair with mesh of pelvic organ prolapse (POP) provides women with the durability of a synthetic graft using the less-invasive route of vaginal surgery. "
09/01/2014 - "Choice of pelvic organ prolapse surgery: vaginal or abdominal, native tissue or synthetic grafts, open abdominal versus laparoscopic or robotic."
|5.||Length of Stay
06/01/2014 - "Abdominal sacrocolpopexy (ASC) represents the superior treatment for apical pelvic organ prolapse (POP) but is associated with increased length of stay, analgesic requirement, and cost compared with transvaginal procedures. "
03/01/2015 - "Variables analyzed included sex, age, diagnosis, associated pelvic organ prolapse, comorbidities, length of stay, complications (Clavien-Dindo scale), and mortality. "