HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Coordination Complexes

Neutral or negatively charged ligands bonded to metal cations or neutral atoms. The number of ligand atoms to which the metal center is directly bonded is the metal cation's coordination number, and this number is always greater than the regular valence or oxidation number of the metal. A coordination complex can be negative, neutral, or positively charged.
Also Known As:
Metal Complexes; Complexes, Coordination; Complexes, Metal
Networked: 576 relevant articles (21 outcomes, 60 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Chen, Tianfeng: 9 articles (03/2022 - 08/2014)
2. Ma, Dik-Lung: 8 articles (10/2020 - 11/2007)
3. Leung, Chung-Hang: 7 articles (10/2020 - 07/2013)
4. Keppler, Bernhard K: 7 articles (08/2019 - 06/2003)
5. Hartinger, Christian G: 6 articles (03/2020 - 06/2003)
6. Gust, Ronald: 5 articles (07/2022 - 03/2007)
7. Ott, Ingo: 5 articles (03/2020 - 03/2007)
8. Shrivastav, Anuraag: 5 articles (09/2006 - 04/2002)
9. Banerjee, Samya: 4 articles (04/2022 - 07/2015)
10. Wilson, Justin J: 4 articles (01/2021 - 03/2020)

Related Diseases

1. Neoplasms (Cancer)
2. Hepatocellular Carcinoma (Hepatoma)
04/30/2023 - "Moreover, four examined metal complexes displayed anticancer activity against hepatocellular carcinoma cells (HepG-2) but to different degrees. "
02/01/1980 - "The observed effects of GHL-metal complexes, including stimulation of cellular adhesiveness to substratum (flattening) and intercellular attachment (monolayer formation), appear to satisfy requirements for growth of hepatoma cells in monolayer culture."
12/01/1975 - "Anti-tumour activity of heavy transition metal complexes against hepatoma cells."
11/20/2020 - "The anticancer activity of synthesized metal complexes was evaluated in vitro against two types of cancer cell lines: human breast cancer MCF-7 cells and hepatocellular carcinoma HepG-2 cells. "
05/04/2014 - "The results obtained revealed that: (1) UDCA and its metal complexes in the tested concentrations decreased (to a varying degree) the viability and proliferation of the treated cells in a time- and concentration-dependent manner; (2) chicken hepatoma (LSCC-SF-Mc29) cells were most sensitive to the cytotoxic and antiproliferative action of the compounds tested, followed by rat sarcoma (LSR-SF-SR) cells; (3) Cu‒UDCA and Ni‒UDCA were more effective against animal LSCC-SF-Mc29 and LSR-SF-SR cells, while Zn‒UDCA significantly decreased the viability and proliferation of human tumour cell lines; (4) applied independently, UDCA expressed lower cytotoxic/cytostatic activity as compared to metal complexes; and (5) the sensitivity of the non-tumour embryonic Lep-3 cells to the effects of UDCA and its metal complexes was comparable or even higher than those of the human tumour cells."
3. Chagas Disease (American Trypanosomiasis)
4. Leishmaniasis
5. Pancreatic Neoplasms (Pancreatic Cancer)

Related Drugs and Biologics

1. Ligands
2. Platinum
3. Metals
4. Proteins (Proteins, Gene)
5. Chelating Agents
6. Cisplatin (Platino)
7. Schiff Bases (Schiff Base)
8. Thiosemicarbazones
9. Antineoplastic Agents (Antineoplastics)
10. Iron

Related Therapies and Procedures

1. Therapeutics
2. Precision Medicine
3. Drug Therapy (Chemotherapy)
4. Photochemotherapy (Photodynamic Therapy)
5. Quantum Dots (Quantum Dot)