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Endosomal Sorting Complexes Required for Transport

A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in membrane scission during formation of intraluminal vesicles, during the final step of CYTOKINESIS, and during the budding of enveloped viruses. The ESCRT machinery is comprised of the protein products of Class E vacuolar protein sorting genes.
Also Known As:
ESCRT Complexes; ESCRT I; ESCRT II; ESCRT III; ESCRT Machinery; Endosomal Sorting Complex Required for Transport; Endosomal Sorting Complex Required for Transport I; Endosomal Sorting Complex Required for Transport II; Endosomal Sorting Complex Required for Transport III; Endosomal Sorting Complex Required for Transport Machinery; Complexes, ESCRT; Machinery, ESCRT
Networked: 51 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Lee, Jin-A: 8 articles (01/2015 - 09/2007)
2. Gao, Fen-Biao: 7 articles (02/2014 - 09/2007)
3. Stenmark, Harald: 3 articles (05/2009 - 11/2007)
4. Sadoul, Rémy: 2 articles (02/2015 - 09/2010)
5. Goldberg, Yves: 2 articles (02/2015 - 09/2010)
6. Blot, Béatrice: 2 articles (02/2015 - 09/2010)
7. Han, Jeong-Ho: 2 articles (01/2015 - 05/2012)
8. Jun, Mi-Hee: 2 articles (01/2015 - 05/2012)
9. Jang, Deok-Jin: 2 articles (01/2015 - 05/2012)
10. Ahmad, S Tariq: 2 articles (02/2014 - 09/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Neurodegenerative Diseases (Neurodegenerative Disease)
3. Bacterial Infections (Bacterial Infection)
4. Infection
5. Frontotemporal Dementia

Related Drugs and Biologics

1. Endosomal Sorting Complexes Required for Transport
2. Viral RNA
3. Tsg101 protein
4. Proteins (Proteins, Gene)
5. Interferons
6. Ubiquitinated Proteins
7. Receptor-Interacting Protein Serine-Threonine Kinases
8. Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins
9. N-Ethylmaleimide-Sensitive Proteins (N-Ethylmaleimide-Sensitive Fusion Protein)
10. Ubiquitin