|1.||Neurodegenerative Diseases (Neurodegenerative Disease)
|2.||Pressure Ulcer (Bedsore)
|3.||Neuroaxonal Dystrophies (Neuroaxonal Dystrophy, Late Infantile)
|4.||Nervous System Diseases (Neurological Disorders)
|5.||Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
|1.||Opal, Puneet: 2 articles (05/2013 - 01/2013)|
|2.||Goldman, Robert D: 2 articles (05/2013 - 01/2013)|
|3.||Tibshirani, Michael: 1 article (06/2015)|
|4.||Durham, Heather D: 1 article (06/2015)|
|5.||Gentil, Benoit J: 1 article (06/2015)|
|6.||Garcia Diaz, Alejandro: 1 article (01/2015)|
|7.||Wichterle, Hynek: 1 article (01/2015)|
|8.||Ekins, Sean: 1 article (01/2015)|
|9.||Johnson-Kerner, Bethany L: 1 article (01/2015)|
|10.||Bharath, M M Srinivas: 1 article (02/2014)|
|1.||Oxandrolone (Anavar)FDA LinkGeneric
07/01/2009 - "Chemical disruption of the vimentin network with acrylamide, intermediate filament bundling in cells from a patient with giant axonal neuropathy, and absence of vimentin in fibroblasts from vimentin(-/-) mice severely reduced entry of either strain. "
01/01/1996 - "Aggregation of a subpopulation of vimentin filaments in cultured human skin fibroblasts derived from patients with giant axonal neuropathy."
02/01/1990 - "Giant axonal neuropathy (GAN) is a disorder characterized pathologically by distal neurofilament-filled bulbous swellings in axons, and widespread collection of intermediate filaments, including masses of vimentin filaments in cultured skin fibroblasts. "
11/01/1984 - "Giant axonal neuropathy skin fibroblasts, which are characterized by a selective and partial disorganization of vimentin filaments  exhibited, when compared with normal skin fibroblasts, less fibrin clot retractile (FCR) activity and spreading within the fibrin clot both during active growth and resting stage. "
11/01/1998 - "The present results suggest that high doses of n-hexane cause a diffuse IF disorder in a similar form as occurs in giant axonal neuropathy. "
10/01/1976 - "These morphologic features are identical to those produced in experimental animals after exposure to these chemicals and are similar to those found in n-hexane neuropathy and in the three reported cases of giant axonal neuropathy. "
11/01/1983 - "Axonal swellings associated with large aggregates of neurofilaments are characteristic of neuropathies caused by chemical neurotoxins (n-hexane, methyl n-butyl ketone, and acrylamide) or giant axonal neuropathy (GAN--an autosomal recessive genetic disease). "
|4.||Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
05/01/2013 - "Giant axonal neuropathy (GAN) is an early-onset neurological disorder caused by mutations in the GAN gene (encoding for gigaxonin), which is predicted to be an E3 ligase adaptor. "
01/01/2013 - "Giant axonal neuropathy (GAN)(1) is a rare autosomal recessive neurological disorder caused by mutations in the GAN gene that encodes gigaxonin, a member of the BTB/Kelch family of E3 ligase adaptor proteins.(1) This disease is characterized by the aggregation of Intermediate Filaments (IF)-cytoskeletal elements that play important roles in cell physiology including the regulation of cell shape, motility, mechanics and intra-cellular signaling. "
06/01/1993 - "The neuropathy produced by the hexacarbon 2,5-hexanedione (2,5-HD) resembles human and canine inherited giant axonal neuropathy (GAN) in the presence of giant axonal swellings that contain accumulations of neurofilaments. "
02/01/1985 - "The 2,5-hexanedione axon may provide insight into the pathogenesis of inherited and acquired giant axonal neuropathies and offers a model to investigate the relationship between number of NF and axonal size in central axons."
02/01/1985 - "Slow axonal transport was studied in the optic systems of rats treated with 2,5-hexanedione, a toxic compound that produces an experimental model of giant axonal neuropathy. "
|9.||Staphylococcal Protein A (A, Protein)IBA
02/01/2007 - "Anesthesia for a child with giant axonal neuropathy."