|1.||Persson, Jenny Liao: 10 articles (06/2013 - 12/2004)|
|2.||Müller-Tidow, Carsten: 8 articles (01/2009 - 08/2002)|
|3.||Berdel, Wolfgang E: 5 articles (01/2009 - 02/2003)|
|4.||Ekberg, Jenny: 5 articles (01/2009 - 12/2004)|
|5.||Serve, Hubert: 5 articles (08/2007 - 08/2002)|
|6.||Wolgemuth, Debra J: 4 articles (01/2011 - 02/2004)|
|7.||Bjartell, Anders: 4 articles (07/2008 - 02/2004)|
|8.||Landberg, Göran: 4 articles (03/2006 - 12/2004)|
|9.||Serve, H: 4 articles (04/2001 - 05/2000)|
|10.||Berdel, W E: 4 articles (04/2001 - 05/2000)|
01/01/2014 - "From our previous study, we established that cyclin A1 (CCNA1) promoter methylation is strongly correlated with multistep progression of HPV-associated cervical cancer, suggesting potential use as a diagnostic maker of disease. "
12/01/2013 - "Outstandingly, previous studies have also demonstrated the abnormal expression of cyclin A1 in various human tumors. "
07/01/2011 - "Our previous study explored the very high degree of cyclin A1 (CCNA1) promoter methylation in invasive cervical cancer in which all cases were infected by HPV. "
01/01/2006 - "This methylation study indicated that cyclin A1 is a potential tumor marker for early diagnosis of invasive cervical cancer."
01/01/2006 - "More important, this study demonstrated that not only is cyclin A1 promoter hypermethylation strikingly common in cervical cancer, but is also specific to the invasive phenotype in comparison with other histopathological stages during multistep carcinogenesis. "
03/15/1999 - "In this study, we showed that cyclin A1 was highly expressed in a subset of leukemia samples from patients. "
10/29/2009 - "Cyclin A1 is essential for leukemia progression, and its expression is tightly regulated by acinus, a nuclear speckle protein. "
06/15/2008 - "Ablation of acinus or SRPK2 abrogates cyclin A1 expression in leukemia cells and arrest cells at G(1) phase. "
08/15/2007 - "DNA damage response involves modulation of Ku70 and Rb functions by cyclin A1 in leukemia cells."
02/01/2006 - "Exogenous WTA gene could inhibit the proliferation and colony forming ability of leukemia cells through up-regulating the expression of p21 and Cyclin A1 and arresting cell cycle at S phase."
|3.||Prostatic Neoplasms (Prostate Cancer)
07/16/2008 - "Cyclin A1 is a cell cycle regulator that has been implicated in the progression of prostate cancer. "
09/22/2005 - "However, a role of cyclin A1 in tumorigenesis of prostate cancer has not been reported. "
07/16/2008 - "Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis."
09/22/2005 - "In the present study, expression of cyclin A1 in patients with prostate cancer and a role of cyclin A1 in mediating expression of vascular endothelial growth factor (VEGF) were investigated. "
06/01/2013 - "We correlated LSD1 and JMJD2A expression with known mediators of prostate cancer progression: VEGF-A and cyclin A1. "
08/01/2009 - "In the present study, we performed a mutation screening of the cyclin A1 gene in order to investigate the possible association between the mutations of the gene and human impaired spermatogenesis using denaturing high performance liquid chromatography (DHPLC) in 347 infertile patients with azoospermia or severe oligozoospermia and 210 fertile controls. "
08/01/2002 - "The objective of this study was to establish a classification of meiotic disorders by detection of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and cyclin A1 mRNA in patients presenting with non-obstructive azoospermia. "
|5.||Lung Neoplasms (Lung Cancer)
10/01/2006 - "Our study suggests that cyclin A1 might be a promising anticancer target specific to lung cancer."
10/24/2014 - "Interestingly, doxorubicin upregulated caspase-1 in a concentration-dependent manner, and z-YAVD-fmk, a specific inhibitor of caspase-1, reversed the doxorubicin-induced decrease in cyclin A1 in A549 lung cancer and MCF7 breast cancer cells. "
10/24/2014 - "In the present study, we found that doxorubicin decreased the expression of cyclin A1 at the protein level in A549 lung cancer cells, while markedly downregulating its mRNA levels. "
10/01/2006 - "As with cyclin A1 siRNA in lung cancer cell lines, cyclin B1, Cdc2 and CDK2 were all significantly downregulated. "
10/01/2006 - "In order to explore the possibility of using cyclin A1 and cyclin B1 as anticancer targets, we knocked them down in two lung cancer cell lines, H157 and H596, using siRNA. "
|1.||Messenger RNA (mRNA)
|3.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|5.||Small Interfering RNA (siRNA)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)
|3.||Contraception (Birth Control)