|1.||Finn, Olivera J: 7 articles (09/2009 - 05/2002)|
|2.||Ye, Qinong: 4 articles (10/2015 - 09/2011)|
|3.||Xu, Xiaojie: 4 articles (10/2015 - 09/2011)|
|4.||Zhang, Jian-Ying: 4 articles (01/2014 - 11/2003)|
|5.||Zhan, Qimin: 4 articles (01/2013 - 05/2002)|
|6.||Cho, Nam Hoon: 4 articles (04/2007 - 09/2005)|
|7.||Kang, Suki: 4 articles (04/2007 - 09/2005)|
|8.||Coleman, Nicholas: 4 articles (10/2005 - 10/2003)|
|9.||Bai, M: 4 articles (05/2003 - 04/2001)|
|10.||Agnantis, N J: 4 articles (05/2003 - 04/2001)|
03/01/2006 - "There was significantly greater cyclin B1 expression in invasive cervical cancer than in normal cervical tissue (P = 0.019). "
01/01/2010 - "These results demonstrate a unique anti-apoptotic function of mitochondrial p53 regulated by cyclin B1/Cdk1-mediated Ser-315 phosphorylation in p53-wild-type tumor cells, which may provide insights for improving the efficacy of anti-cancer therapy, especially for tumors that retain p53."
09/01/2008 - "In summary, we propose that cyclin B1 is a biomarker predictive of the efficacy of Chk1 inhibitors across different types of cancers. "
05/01/2015 - "A mechanistic study showed that 17#-induced selective anti-cancer effects were highly dependent on UPR inhibition, and overexpressing GRP78 or XBP1s reversed the 17#-induced growth inhibition and cell cycle arrest, partially by delaying the downregulation of the cell cycle regulator cyclin B1. "
10/01/2014 - "Studies in mice have shown that cyclin B1 vaccine-induced immunity significantly delayed or prevented the spontaneous cancer development later in life. "
|2.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/01/2013 - "Nuclear localization of cyclin B1 is an indicator for cells undergoing mitotic division, and the overexpression has shown promising results as a good prognostic predictor for patients of squamous cell carcinoma (SCC). "
09/01/2006 - "In this study, we evaluated the immunohistochemical expression of cyclin B1 in a series of 40 oral tongue squamous cell carcinomas and analyzed the findings in relation to both clinicopathological variables and the Ki-67 labeling index. "
06/01/2002 - "The objective of the current study was to clarify the role of the cell cycle regulators, cyclin B1 and p53, in patients with esophageal squamous cell carcinoma (ESCC). "
03/01/2002 - "The aim of the present study was to elucidate the biological significance of cyclin B1 expression in squamous cell carcinoma (SCC) of the esophagus. "
02/01/1999 - "The main aim of this study was to examine the relationships between the cyclin B1 expression in human esophageal squamous cell carcinoma (SCC) and clinicopathological factors and prognosis of the patients. "
09/01/2007 - "Our studies demonstrate that primary human AML cells show aberrant cytoplasmic expression of cyclin B1 for a majority of patients and a specific humoral immune response was also detected for a subset of patients with untreated leukemia."
02/01/2000 - "In the present study, FCM was used to compare the localization and the kinetic patterns of cyclin B1 expression in Jurkat leukemia cell line and phytohemagglutinin (PHA)-stimulated normal T lymphocytes. "
10/01/2005 - "Expressions of cyclin B1 and p21cipl in adult acute leukemia and their correlation."
10/01/2003 - "To investigate the clinical significance of cyclin B1 expression in adult acute leukemia (AL) patients. "
10/01/2003 - "[The clinical significance of cyclin B1 expression in adult acute leukemia patients]."
|4.||Neoplasm Metastasis (Metastasis)
03/01/2012 - "Our findings show that the upregulation of BMP4 and BMPR1A in HCC promotes the proliferation and metastasis of HCC cells and that CDK1 and cyclin B1 are important SMAD-independent molecular targets in BMP4 signaling pathways, during the HCC tumorigenesis. "
08/01/2010 - "In addition, the expression of cyclin B1 was associated with regional lymph node metastasis and poor prognosis. "
07/01/2009 - "Increased cyclin B1 and A expression was found in 40.9 and 58.9% of NSCLC cases, respectively, and was significantly higher in primary NSCLC, lymph node metastases and some bronchial precursor lesions compared with normal bronchial epithelium. "
02/01/2008 - "These results establish a mechanistic link between cyclin B1 and ESCC metastasis and provide novel insight into understanding of cyclin B1 in the development of ESCC malignancy."
02/01/2008 - "Notably, altered expression of epithelial markers and mesenchymal markers were observed in the cells overexpressing cyclin B1, suggesting that cyclin B1 contributes to metastasis probably by promoting an epithelial-mesenchymal transition. "
|5.||Colorectal Neoplasms (Colorectal Cancer)
10/01/2004 - "We used immunohistochemical analysis to study the expression and prognostic impact of cyclin B1, a key molecule for G2-M phase transition during the cell cycle, in a series of 342 curatively resected colorectal carcinomas. "
12/01/2015 - "Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes."
03/01/2015 - "Moreover, we demonstrated that AGE delayed cell cycle progression by downregulating cyclin B1 and cdk1 expression via inactivation of NF-κB in the human colorectal cancer cells but did not induce apoptosis. "
01/01/2015 - "Inhibition of Cyclin B1 in colorectal cancer cells enhanced the cell migration and invasion of three different colorectal cancer cell lines. "
01/01/2015 - "The Kaplan-Meier survival analysis proved that low Cyclin B1 expression was associated with poor overall survival of patients with colorectal cancer. "
|1.||Proteins (Proteins, Gene)
|3.||Proliferating Cell Nuclear Antigen (PCNA)
|4.||Cell Cycle Proteins
|5.||Messenger RNA (mRNA)
|7.||polo-like kinase 1
|9.||2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate (AITC)
|10.||Transcription Factor 7-Like 2 Protein
|1.||Drug Therapy (Chemotherapy)
|2.||Heterologous Transplantation (Xenotransplantation)