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Monilethrix

Rare autosomal dominant disorder of the hair shaft. The clinical features of the disease include HYPOTRICHOSIS, dry, and/or brittle hair, with varying degrees of ALOPECIA. Mutations in the hair-specific keratin genes KRTHB1, KRTHB3, or KRTHB6 are associated with monilethrix. Autosomal recessive monilethrix with limited HYPOTRICHOSIS are also known. Mutations in Dsg4, Liph, and P2ry5 protein genes are associated with the recessive form of monilethrix.
Also Known As:
Hair, Nodose; Hairs, Nodose; Monilethrices; Nodose Hairs; Nodose Hair
Networked: 72 relevant articles (5 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hypotrichosis
2. Alopecia (Baldness)
3. Ichthyosis Bullosa of Siemens
4. Pachyonychia Congenita (Jadassohn-Lewandowsky Syndrome)
5. Epidermolytic Palmoplantar Keratoderma

Experts

1. Zlotogorski, A: 3 articles (06/2012 - 09/2000)
2. Christiano, Angela M: 3 articles (12/2009 - 12/2003)
3. Miteva, Mariya: 2 articles (09/2016 - 09/2016)
4. Singh, Gaurav: 2 articles (09/2016 - 09/2016)
5. Sinclair, Rodney: 2 articles (05/2016 - 12/2003)
6. Betz, R C: 2 articles (10/2015 - 06/2014)
7. Horev, L: 2 articles (06/2012 - 09/2000)
8. Sinclair, R: 2 articles (06/2012 - 06/2012)
9. Bazzi, Hisham: 2 articles (12/2009 - 06/2006)
10. Horev, Liran: 2 articles (06/2006 - 12/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Monilethrix:
1. Minoxidil (Rogaine)FDA LinkGeneric
2. RetinoidsIBA
3. AcitretinFDA Link
4. Keratins (Keratin)IBA
5. Type II Keratins (Type II Keratin)IBA
6. DNA (Deoxyribonucleic Acid)IBA
7. Hair-Specific Keratins (Keratins, Hair Specific)IBA
8. DesmogleinsIBA
9. Keratin-6 (Keratin 6A)IBA
10. Glutamic Acid (Glutamate)FDA Link

Therapies and Procedures

1. Traction
2. Therapeutics
3. Drug Therapy (Chemotherapy)
4. Aftercare (After-Treatment)