Cathepsin W

A cysteine endopeptidase found in NATURAL KILLER CELLS and CYTOTOXIC T-LYMPHOCYTES. It may have a specific function in the mechanism or regulation of cytolytic activity of immune cells.

Also Known As:

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Malfertheiner, Peter: 3 articles (12/2011 - 07/2002)
2.	Weber, Ekkehard: 3 articles (12/2011 - 07/2002)
3.	Wex, Thomas: 3 articles (12/2011 - 07/2002)
4.	Kahl, Stefan: 2 articles (10/2005 - 07/2002)
5.	Ban, Dongjo: 1 article (01/2022)
6.	Jordan, I King: 1 article (01/2022)
7.	Lee, Kara Keun: 1 article (01/2022)
8.	Mariño-Ramírez, Leonardo: 1 article (01/2022)
9.	McDonald, John F: 1 article (01/2022)
10.	Nagar, Shashwat Deepali: 1 article (01/2022)

Related Diseases

1.	Neoplasm Metastasis (Metastasis) 01/01/2023 - "Western-blot and Transwell assay were utilized to explore the role of fatty acid binding protein 4 (FABP4) / cathepsin W (CTSW) in CRC metastasis and immunity. " 02/17/2023 - "Moreover, 348 altered proteins were observed, among which several metastasis-specific markers, including cathepsin W (CATW), magnesium transporter MRS2 (MRS2), syntenin-2 (SDCB2), reticulon-4 (RTN), and UV excision repair protein RAD23 homolog (RAD23B), were also identified. "
2.	Gastritis 07/01/2002 - "In autoimmune gastritis, cathepsin W-expressing cells made up for 65% of all CD45+ cells, whereas the corresponding values for CD and UC were 11% and 6%, respectively. " 10/14/2005 - "Upregulation of cathepsin W-expressing T cells is specific for autoimmune atrophic gastritis compared to other types of chronic gastritis." 07/01/2002 - "Notably, samples from patients suffering from chronic inflammatory bowel disease (Crohn's disease, CD; ulcerative coliltis, UC) or autoimmune gastritis revealed variable amounts of cathepsin W-expressing cells. "
3.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 07/01/2002 - "Notably, samples from patients suffering from chronic inflammatory bowel disease (Crohn's disease, CD; ulcerative coliltis, UC) or autoimmune gastritis revealed variable amounts of cathepsin W-expressing cells. "
4.	Tuberculosis (Tuberculoses) 09/01/2006 - "Altered expression of the genes for TNF-alpha, cathepsin W and TNFRSF7 may be risk factors for the extrapulmonary dissemination of tuberculosis in humans."
5.	Pancreatic Neoplasms (Pancreatic Cancer) 10/04/2023 - "Down regulation of Cathepsin W is associated with poor prognosis in pancreatic cancer."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Cysteine Proteases (Cysteine Protease)
3.	Syntenins
4.	Fatty Acid-Binding Proteins
5.	Lectins
6.	Protein Isoforms (Isoforms)
7.	Glutamic Acid (Glutamate)
8.	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
9.	Biomarkers (Surrogate Marker)
10.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)