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Cathepsin K

A cysteine protease that is highly expressed in OSTEOCLASTS and plays an essential role in BONE RESORPTION as a potent EXTRACELLULAR MATRIX-degrading enzyme.
Networked: 569 relevant articles (21 outcomes, 73 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Brömme, Dieter: 17 articles (01/2016 - 03/2002)
2. Saftig, Paul: 11 articles (04/2013 - 06/2004)
3. Duong, Le T: 10 articles (12/2014 - 01/2011)
4. Shi, Guo-Ping: 9 articles (06/2015 - 03/2007)
5. Kiviranta, Riku: 9 articles (02/2015 - 01/2005)
6. Martignoni, Guido: 7 articles (03/2015 - 02/2009)
7. Pickarski, Maureen: 7 articles (12/2014 - 01/2008)
8. Deacon, Steve: 7 articles (08/2014 - 06/2011)
9. Small, Maria: 7 articles (08/2014 - 06/2011)
10. Nagase, Shinichi: 7 articles (08/2014 - 06/2011)

Related Diseases

1. Osteoporosis
2. Bone Resorption
3. Postmenopausal Osteoporosis
4. Inflammation
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. odanacatib
2. Collagen
3. Phosphotransferases (Kinase)
4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
5. Chalcones
6. Proteasome Endopeptidase Complex (Proteasome)
7. Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)
8. P-Glycoprotein
9. Tubulin
10. Oxidoreductases

Related Therapies and Procedures

1. Rectal Administration
2. Ligation
3. Aftercare (After-Treatment)
4. Drug Therapy (Chemotherapy)
5. Tooth Movement