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Acute Chest Syndrome

Respiratory syndrome characterized by the appearance of a new pulmonary infiltrate on chest x-ray, accompanied by symptoms of fever, cough, chest pain, tachypnea, or DYSPNEA, often seen in patients with SICKLE CELL ANEMIA. Multiple factors (e.g., infection, and pulmonary FAT EMBOLISM) may contribute to the development of the syndrome.
Also Known As:
Acute Chest Syndromes; Syndrome, Acute Chest; Syndromes, Acute Chest
Networked: 202 relevant articles (13 outcomes, 23 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pain (Aches)
2. Sickle Cell Anemia (Hemoglobin S Disease)
3. Pulmonary Hypertension (Ayerza Syndrome)
4. Necrosis
5. Stroke (Strokes)

Experts

1. Miller, Scott T: 9 articles (04/2013 - 10/2003)
2. Wang, Winfred C: 7 articles (12/2014 - 10/2003)
3. Ware, Russell E: 7 articles (12/2014 - 01/2009)
4. Casella, James F: 7 articles (10/2013 - 11/2006)
5. Gordeuk, Victor R: 6 articles (10/2015 - 08/2008)
6. DeBaun, Michael R: 6 articles (09/2015 - 11/2006)
7. Ballas, Samir K: 6 articles (03/2015 - 01/2002)
8. Knight-Madden, Jennifer M: 6 articles (01/2015 - 01/2012)
9. Ataga, Kenneth I: 5 articles (12/2014 - 10/2011)
10. Kato, Gregory J: 5 articles (07/2013 - 05/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Acute Chest Syndrome:
1. Hydroxyurea (Hydrea)FDA LinkGeneric
2. Nitric Oxide (Nitrogen Monoxide)FDA Link
3. Bronchodilator Agents (Bronchodilators)IBA
4. Arginine (L-Arginine)FDA Link
5. Heme Oxygenase-1IBA
6. Hemoglobins (Hemoglobin)IBA
7. Sickle HemoglobinIBA
8. Biological Markers (Surrogate Marker)IBA
9. Poloxamer (Poloxamer 407)IBA
10. alpha-GlobinsIBA

Therapies and Procedures

1. Blood Transfusion (Blood Transfusions)
2. Splenectomy
3. Contraception (Birth Control)
4. Extracorporeal Membrane Oxygenation (ECMO)
5. Transplantation (Transplant Recipients)