|1.||Remuzzi, Giuseppe: 2 articles (07/2015 - 01/2010)|
|2.||Benigni, Ariela: 2 articles (07/2015 - 01/2010)|
|3.||Zeng, Heng: 2 articles (01/2015 - 02/2014)|
|4.||He, Xiaochen: 2 articles (01/2015 - 02/2014)|
|5.||Chen, Jian-Xiong: 2 articles (01/2015 - 02/2014)|
|6.||Hou, Xuwei: 2 articles (01/2015 - 02/2014)|
|7.||Tang, Zhiwei: 1 article (11/2015)|
|8.||Han, Pengcheng: 1 article (11/2015)|
|9.||Yin, Junxiang: 1 article (11/2015)|
|10.||Liu, Qingwei: 1 article (11/2015)|
02/15/2014 - "Our recent study shows that apelin may protect ischemic heart failure via upregulation of sirtuin 3 (Sirt3) and angiogenesis. "
01/01/2010 - "The absence of AT(1A) protected multiple organs from oxidative damage and the alleviation of aging-like phenotype was associated with increased number of mitochondria and upregulation of the prosurvival gene sirtuin 3. AT(1) receptor antagonists have been proven safe and well-tolerated for chronic use and are used as a key component of the modern therapy for hypertension and cardiac failure, therefore Ang II/AT(1) pathway represents a feasible therapeutic strategy to prolong life span in humans."
01/01/2015 - "CAEA treatment recovered sirtuin 1 and sirtuin 3 activity, and attenuated the changes of proteins, including manganese superoxide dismutase and hypoxia-inducible factor 1-α, which are the most likely mechanisms responsible for the alleviation of isoproterenol-caused cardiac injury CAEA prevents catecholamine-induced cardiac damage and is therefore a possible new therapeutic approach for preventing heart failure progression."
|3.||Breast Neoplasms (Breast Cancer)
01/01/2014 - "To investigate the association of Sirtuin 3 (SIRT 3) expression between the clinical characteristics and prognosis in breast cancer patients. "
01/01/2015 - "Here, we show that oroxylin A inhibits glycolysis in breast cancer cells via the Sirtuin 3 (SIRT3)-mediated destabilization of hypoxia-inducible factor 1α (HIF1α), which controls glycolytic gene expression. "
09/15/2013 - "Identification of Sirtuin 3, a mitochondrial protein deacetylase, as a new contributor to tamoxifen resistance in breast cancer cells."
09/15/2013 - "The current study reports a previously unappreciated role of Sirtuin 3 (SIRT3), a mitochondrial protein deacetylase, in altering sensitivity of breast cancer cells to tamoxifen (Tam), a commonly used anti-estrogen agent. "
08/01/2013 - "Results showed that tumors with a low ERα/ERβ ratio have greater oxidative damage and higher antioxidant enzyme protein levels, as well as uncoupling protein (UCP) and sirtuin 3 (SIRT3), and have high studied signaling pathway activation. "
01/01/2014 - "Sirtuin 3 (Sirt3), one of the seven Sirtuins family members, plays critical roles in the progression of multiple cancer types. "
08/01/2015 - "Sirtuin deacetylases remove acetyl groups from modified lysine residues, and sirtuin 3 (SIRT3) has been identified as a target for cancer therapeutics. "
|2.||Mitochondrial Proteins (Mitochondrial Protein)
|6.||Proteins (Proteins, Gene)
|8.||AMP-Activated Protein Kinases
|9.||Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
|10.||Hypoxia-Inducible Factor 1