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Sirtuin 1

A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
Also Known As:
Silent Mating Type Information Regulation 2 Homolog 1
Networked: 208 relevant articles (13 outcomes, 23 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Chen, Rui: 5 articles (01/2015 - 03/2009)
2. Yao, Hongwei: 4 articles (12/2015 - 09/2010)
3. Rahman, Irfan: 4 articles (12/2015 - 09/2010)
4. You, Min: 4 articles (04/2015 - 03/2008)
5. Hogg, Richard T: 4 articles (01/2015 - 06/2009)
6. Garcia, Joseph A: 4 articles (01/2015 - 06/2009)
7. Gerard, Robert D: 4 articles (01/2015 - 06/2009)
8. Sundar, Isaac K: 3 articles (12/2015 - 06/2012)
9. Wang, Xiang-Dong: 3 articles (04/2015 - 04/2013)
10. Chen, Jun: 3 articles (12/2014 - 02/2014)

Related Diseases

1. Atherosclerosis
2. Atrophy
3. Anoxia (Hypoxia)
4. Neurodegenerative Diseases (Neurodegenerative Disease)
5. Huntington Disease (Huntington's Disease)

Related Drugs and Biologics

1. resveratrol
2. Histone Deacetylases (Histone Deacetylase)
3. NAD (NADH)
4. Caspase 3 (Caspase-3)
5. Staphylococcal Protein A (A, Protein)
6. Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)
7. Metformin (Glucophage)
8. AMP-Activated Protein Kinases
9. Transcription Factors (Transcription Factor)
10. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)