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Jumonji Domain-Containing Histone Demethylases

A family of histone demethylases that share a conserved Jumonji C domain. The enzymes function via an iron-dependent dioxygenase mechanism that couples the conversion of 2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.
Also Known As:
JmjC Domain-Containing Histone Demethylases; JmjC Domain Containing Histone Demethylases; Jumonji Domain Containing Histone Demethylases
Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Yang, M: 1 article (05/2014)
2. Pollard, P J: 1 article (05/2014)
3. Soga, T: 1 article (05/2014)
4. Adam, J: 1 article (05/2014)
5. Schofield, Christopher J: 1 article (12/2008)
6. Loenarz, Christoph: 1 article (12/2008)
7. Mole, David R: 1 article (12/2008)
8. Gleadle, Jonathan M: 1 article (12/2008)
9. McDonough, Michael A: 1 article (12/2008)
10. Pollard, Patrick J: 1 article (12/2008)

Related Diseases

1. Anoxia (Hypoxia)
2. Neoplasms (Cancer)

Related Drugs and Biologics

1. Dioxygenases
2. Mixed Function Oxygenases (Monooxygenases)
3. DNA (Deoxyribonucleic Acid)
4. Cytosine