Retinoblastoma-Binding Protein 1

A ubiquitously expressed regulatory protein that contains a retinoblastoma protein binding domain and an AT-rich interactive domain. The protein may play a role in recruiting HISTONE DEACETYLASES to the site of RETINOBLASTOMA PROTEIN-containing transcriptional repressor complexes.

Also Known As:

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Feng, Yingang: 3 articles (01/2019 - 03/2012)
2.	Gong, Weibin: 3 articles (01/2019 - 03/2012)
3.	Perrett, Sarah: 3 articles (01/2019 - 03/2012)
4.	Wang, Jinfeng: 2 articles (02/2014 - 03/2012)
5.	Liang, Qihui: 1 article (01/2019)
6.	Tong, Yufeng: 1 article (01/2019)
7.	Yao, Xingzhe: 1 article (01/2019)
8.	Mo, Jinjin: 1 article (03/2012)
9.	Zhou, Tao: 1 article (03/2012)
10.	Carrozza, Michael J: 1 article (01/2004)

Related Diseases

1.	Leukemia 01/01/2019 - "Retinoblastoma-binding protein 1 (RBBP1), also known as AT-rich interaction domain 4A (ARID4A), is a tumour suppressor involved in the regulation of the epigenetic programming in leukemia and Prader-Willi/Angelman syndromes. " 03/09/2012 - "Retinoblastoma-binding protein 1 (RBBP1), also named AT-rich interaction domain containing 4A (ARID4A), is a tumor and leukemia suppressor involved in epigenetic regulation in leukemia and Prader-Willi/Angelman syndromes. " 02/21/2014 - "Retinoblastoma-binding protein 1 (RBBP1) is a tumor and leukemia suppressor that binds both methylated histone tails and DNA. "
2.	Neoplasms (Cancer) 03/09/2012 - "Retinoblastoma-binding protein 1 (RBBP1), also named AT-rich interaction domain containing 4A (ARID4A), is a tumor and leukemia suppressor involved in epigenetic regulation in leukemia and Prader-Willi/Angelman syndromes. " 02/21/2014 - "Retinoblastoma-binding protein 1 (RBBP1) is a tumor and leukemia suppressor that binds both methylated histone tails and DNA. "
3.	Breast Neoplasms (Breast Cancer) 09/01/1999 - "Cytotoxic T lymphocytes that recognize decameric peptide sequences of retinoblastoma binding protein 1 (RBP-1) associated with human breast cancer." 01/09/2004 - "Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription."
4.	Retinoblastoma (Glioblastoma, Retinal) 09/01/1999 - "Retinoblastoma binding protein 1 (RBP-1) is a 143-kDa nuclear phosphoprotein that promotes cell growth by inhibiting the product of retinoblastoma tumour suppressor gene (pRB). "
5.	Neoplasm Metastasis (Metastasis) 01/09/2004 - "Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription."

Related Drugs and Biologics

1.	Phosphoproteins
2.	Peptides (Polypeptides)
3.	Histones (Histone)
4.	Histone Deacetylases (Histone Deacetylase)
5.	DNA (Deoxyribonucleic Acid)