|1.||Kumar, Rakesh: 8 articles (12/2014 - 10/2009)|
|2.||Li, Da-Qiang: 7 articles (12/2014 - 10/2009)|
|3.||Wade, Paul A: 5 articles (10/2013 - 04/2003)|
|4.||Pakala, Suresh B: 4 articles (01/2012 - 10/2009)|
|5.||Levenson, Anait S: 3 articles (02/2015 - 04/2010)|
|6.||Reddy, Sirigiri Divijendra Natha: 3 articles (07/2010 - 10/2009)|
|7.||Ohshiro, Kazufumi: 3 articles (06/2010 - 10/2009)|
|8.||Fujita, Naoyuki: 3 articles (12/2004 - 04/2003)|
|9.||Kajita, Masahiro: 3 articles (12/2004 - 04/2003)|
|10.||Dhar, Swati: 2 articles (02/2015 - 01/2013)|
01/01/2016 - "In studies here, representative molecules from four chemical classes, representing several distinct primary mechanisms of action, were investigated for effects on γ-globin transcriptional repressors, including components of the NuRD complex (LSD1 and HDACs 2-3), and the downstream repressor BCL11A, in erythroid progenitors from hemoglobinopathy patients. "
|2.||Neoplasm Metastasis (Metastasis)
06/25/2010 - "MTA1 (metastasis-associated protein 1), an integral component of the nucleosome remodeling and deacetylase complex, has recently been implicated in the ionizing radiation-induced DNA damage response. "
06/01/2010 - "Recent findings reveal that metastasis-associated protein 1 (MTA1), an integral component of the Mi-2/NuRD complex, has successfully made inroads into DNA damage response pathway, and thus, links two previously unconnected Mi-2/NuRD complex and DNA damage response research areas. "
05/16/2008 - "To understand the biological function of the NuRD complex, we generated a knock-out mouse model of the Mta2 (metastasis-associated protein 2) gene, which encodes a NuRD-specific component. "
11/16/2000 - "We have also purified a p53 target protein in the deacetylase complexes (designated PID; but identical to metastasis-associated protein 2 (MTA2)), which has been identified as a component of the NuRD complex. "
08/01/1999 - "A novel polypeptide highly related to the metastasis-associated protein 1, MTA2, and the methyl-CpG-binding domain-containing protein, MBD3, were found to be subunits of the NuRD complex. "
01/01/2011 - "Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer)."
11/16/2009 - "The Mi-2/NuRD complex: a critical epigenetic regulator of hematopoietic development, differentiation and cancer."
02/01/2015 - "As a component of the nuclear remodeling and deacetylation complex (NuRD complex), metastasis-associated gene 1 (MTA1) has been reported to play a key role in cancer malignancy. "
02/01/2011 - "These findings not only provide novel mechanistic and functional links between TWIST and the Mi2/NuRD complex but also establish new essential roles for the components of Mi2/NuRD complex in cancer metastasis."
08/08/2013 - "We showed that RBB recruits the NuRD complex to the internal promoter of HDM2 and inhibits the expression of MDM2 protein, leading to subsequent stabilization of tumor suppressor p53. "
|4.||Breast Neoplasms (Breast Cancer)
04/18/2003 - "MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer."
11/01/2011 - "Our findings indicate that CCL14 is a critical mediator of the JARID1B/LSD1/NuRD complex in regulation of angiogenesis and metastasis in breast cancer, identifying a novel potential therapeutic target for breast cancer intervention."
08/21/2009 - "LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer."
12/01/2004 - "In breast cancer cells, MTA3 and the Mi-2/NuRD complex mediate repression of Snail, a transcription factor that promotes epithelial to mesenchymal transitions. "
03/01/2014 - "In estrogen-sensitive breast cancer, high levels of E-cadherin fit with high levels of ERα and MTA3 (a component of the transcription Mi-2/NuRD complex with intrinsic DAC activity). "
|5.||Prostatic Neoplasms (Prostate Cancer)
02/01/2015 - "Resveratrol regulates PTEN/Akt pathway through inhibition of MTA1/HDAC unit of the NuRD complex in prostate cancer."
01/01/2013 - "We identified resveratrol as a regulator of MTA1/NuRD complex and re-activator of p53 acetylation in prostate cancer (PCa). "
04/01/2010 - "Resveratrol enhances p53 acetylation and apoptosis in prostate cancer by inhibiting MTA1/NuRD complex."
08/19/2013 - "Here we report the upregulated expression of metastasis-associated protein 1 (MTA1), a component of the nucleosome remodeling deacetylation (NuRD) complex, in chemoresistant prostate cancer (PCa). "
|3.||Histone Deacetylases (Histone Deacetylase)
|5.||Proteins (Proteins, Gene)
|8.||DNA (Deoxyribonucleic Acid)