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Intervertebral Disk Degeneration

Degenerative changes in the INTERVERTEBRAL DISK due to aging or structural damage, especially to the vertebral end-plates.
Also Known As:
Disc Degeneration; Disc Degradation; Degeneration, Disc; Degeneration, Intervertebral Disk; Degenerations, Disc; Degenerations, Intervertebral Disk; Degradation, Disc; Degradations, Disc; Disc Degenerations; Disc Degradations; Disk Degeneration, Intervertebral; Disk Degenerations, Intervertebral; Intervertebral Disk Degenerations; Degenerative Intervertebral Disks
Networked: 541 relevant articles (25 outcomes, 95 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pain (Aches)
2. Low Back Pain (Lumbago)
3. Osteoarthritis
4. Spondylolisthesis
5. Back Pain (Backache)

Experts

1. Hanley, Edward N: 20 articles (06/2015 - 02/2002)
2. Gruber, Helen E: 20 articles (06/2015 - 02/2002)
3. An, Howard S: 13 articles (09/2013 - 06/2002)
4. Hoelscher, Gretchen L: 12 articles (06/2015 - 01/2009)
5. Ingram, Jane A: 10 articles (06/2015 - 03/2005)
6. Mochida, Joji: 10 articles (10/2010 - 01/2003)
7. Norton, H James: 9 articles (04/2014 - 02/2002)
8. Masuda, Koichi: 9 articles (10/2011 - 06/2002)
9. Elliott, Dawn M: 8 articles (07/2014 - 05/2006)
10. Hutton, William C: 8 articles (03/2014 - 01/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Intervertebral Disk Degeneration:
1. Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
2. Proteoglycans (Proteoglycan)IBA
3. CytokinesIBA
4. Biological Markers (Surrogate Marker)IBA
5. Bone Morphogenetic Protein 7IBA
6. Insulin-Like Growth Factor I (IGF-1)IBA
7. Caspase 9IBA
8. Proteins (Proteins, Gene)IBA
9. Glucosamine (Dona)IBA
10. Interleukin-17 (Interleukin 27)IBA

Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Diskectomy (Discectomy)
3. Therapeutics
4. Vertebroplasty
5. Epidural Injections