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Corneal Endothelial Cell Loss

Loss of CORNEAL ENDOTHELIUM usually following intraocular surgery (e.g., cataract surgery) or due to FUCHS' ENDOTHELIAL DYSTROPHY; ANGLE-CLOSURE GLAUCOMA; IRITIS; or aging.
Also Known As:
Corneal Endothelial Cell Damage; Endothelial Cell Loss, Corneal
Networked: 205 relevant articles (9 outcomes, 16 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Cataract (Cataracts)
2. Miosis
3. Corneal Edema
4. Glaucoma
5. Aphakia

Experts

1. Benetz, Beth Ann: 3 articles (12/2019 - 12/2017)
2. Lass, Jonathan H: 3 articles (12/2019 - 04/2008)
3. Maeda, Naoyuki: 3 articles (11/2019 - 01/2008)
4. Patel, Sanjay V: 3 articles (12/2017 - 11/2009)
5. Omulecki, Wojciech: 3 articles (09/2016 - 09/2009)
6. Joo, Choun-Ki: 3 articles (05/2009 - 11/2004)
7. Sandoval, Helga P: 3 articles (10/2006 - 02/2004)
8. Solomon, Kerry D: 3 articles (10/2006 - 02/2004)
9. Dewan, Taru: 2 articles (04/2022 - 01/2019)
10. Inoue, Yoshitsugu: 2 articles (01/2022 - 11/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Corneal Endothelial Cell Loss:
1. Hyaluronic Acid (Hyaluronan)IBA
01/01/1981 - "Of 102 consecutive cases of extracapsular cataract extraction with lens implantation, 54 with the use of Healon, it was found that Healon could induce a reduction of central corneal endothelial cell loss from 29 to 17 per cent and that the only associated complication was a one-day rise of intraocular pressure."
09/01/2007 - "To compare the efficacy of 2.5% sodium hyaluronate (BD Multivisc) with the soft shell technique in reducing corneal endothelial cell damage during cataract phacoemulsification in patients with hard lens nucleus (3+) and cornea guttata. "
04/01/2004 - "Hyaluronan decreased by about 58-60% free-radical formation during phacoemulsification, reduced by about 76-80% modifications in mean corneal thickness and by about 54-61% the corneal endothelial cell loss in all molecular weight ranges used. "
02/01/2008 - "To compare the efficacy of the dispersive-viscoadaptive soft-shell technique using Viscoat and Healon 5 to the dispersive-cohesive soft-shell technique in reducing corneal endothelial cell damage during cataract surgery. "
03/01/1993 - "In the present work, in order to ascertain the endothelial cell protection from viscoelastic substances, we have studied experimental corneal endothelial cell damage caused in the rabbit eye after intracameral injection of different H2O2 concentrations, with and without previous filling and washing out of two widely used viscoelastic substances from the anterior chamber such as 1% sodium hyaluronate (Healon) and hydroxypropylmethylcellulose (HPMC). "
2. sodium hyaluronate drug combination chondroitin sulfateIBA
3. Disinfectants (Biocides)IBA
4. Tamsulosin (Flomax)FDA LinkGeneric
5. 4-toluenesulfonyl fluoride (TSF)IBA
6. SolutionsIBA
7. Phenylephrine (Neo-Synephrine)FDA LinkGeneric
8. MioticsIBA
9. SaltsIBA
10. Mitomycin (Mitomycin-C)FDA LinkGeneric

Therapies and Procedures

1. Air Bags (Airbags)
2. Phacoemulsification
3. Trabeculectomy (Trabeculoplasty)
4. Phakic Intraocular Lenses
5. Filtering Surgery