|1.||Sentman, Charles L: 10 articles (01/2015 - 05/2007)|
|2.||Zhang, Tong: 7 articles (11/2014 - 05/2007)|
|3.||Spies, Thomas: 7 articles (01/2014 - 04/2003)|
|4.||Barber, Amorette: 6 articles (02/2015 - 05/2007)|
|5.||Steinle, Alexander: 6 articles (01/2015 - 08/2004)|
|6.||Lanier, Lewis L: 6 articles (10/2014 - 08/2005)|
|7.||Groh, Veronika: 6 articles (01/2014 - 08/2005)|
|8.||Raulet, David H: 5 articles (01/2015 - 02/2003)|
|9.||Reyburn, Hugh T: 5 articles (08/2014 - 03/2006)|
|10.||Colonna, Marco: 5 articles (05/2011 - 08/2005)|
03/01/2013 - "In this study, we show that murine tumor vasculature expresses Rae1, a ligand for a stimulatory NK receptor NKG2D. "
01/01/2012 - "The goal of this study was to determine whether the NKG2D receptor is down-modulated by cell-cell contact with cervical cancer cells and whether this down-modulation might be associated with changes in NK cell activity. "
01/01/2008 - "In this study, we show that treatment with T cells expressing a chimeric NKG2D receptor (chNKG2D) was able to lead to long-term, tumor-free survival in mice bearing established ovarian tumors. "
04/15/2015 - "The activating receptor NKG2D is particularly relevant for cancer immunosurveillance. "
02/01/2015 - "These data show that compared to CD28 costimulation, activation through the NKG2D receptor leads to the differential activation of the NF-κB signaling pathway and potentially enhances the anti-tumor and anti-viral functions of effector CD8(+) T cells. "
03/01/2008 - "The present study was undertaken to reveal the functional contributions of the activating NKG2D receptor in host defense and disease following JHMV infection. "
05/01/2006 - "In this study, we investigated the physiologic importance of NKG2D receptor-ligand interactions in response to acute pulmonary Pseudomonas aeruginosa infection. "
01/01/2013 - "After viral infection or malignant transformation, unhealthy cells can be directly sensed by natural killer (NK) and some T cells via the activating receptor NKG2D. "
06/24/2010 - "The NKG2D receptor activates natural killer (NK) cell cytotoxicity and cytokine production on recognition of self-molecules induced by cellular stress under different conditions such as viral infections. "
09/01/2009 - "Phenotypic changes in HCV(+) patients were associated with enhanced cytokine-induced cytolytic activity and increased usage of natural cytotoxicity and NKG2D receptor pathways, accompanied by defective cytokine production, although to a lesser extent than patients with chronic HBV infection. "
09/01/2015 - "Here, we study the role of the NK group 2D (NKG2D) receptor for the immunosurveillance of lymphoma. "
11/15/2007 - "In this study, the efficacy and mechanisms of chimeric NKG2D receptor (chNKG2D)-modified T cells in eliminating NKG2D ligand-positive RMA/Rae1 lymphoma cells were evaluated. "
09/01/2015 - "This indicates that NK cells and the NKG2D receptor play a role for control of lymphomas and that selection for NKG2D-L loss mutants provides a mechanism of tumor escape. "
01/01/2011 - "In this report we have used Jurkat and Raji cell lines as a model for studies of the NKG2D receptor-ligand system in T-and B cell leukemia/lymphoma. "
01/01/2014 - "Stress-related immunity can be triggered both in Hodgkin's (HL) and non-Hodgkin lymphomas (NHL), through the activation of the NKG2D receptor on CD8+ T and gammadelta T lymphocytes, by NKG2D-ligands (NKG2D-L), as the MHC class-I related molecules MIC-A/B and the UL16-binding proteins 1-4 (ULBPs), expressed on lymphoma cells. "
|4.||Melanoma (Melanoma, Malignant)
12/01/2011 - "Furthermore, these melanoma patients have a significant decrease in the expression of activating NKG2D receptor, which positively correlates with NK cytotoxicity, and a significant increase in the expression of inhibitory CD158b on CD3-CD56+ NK cells compared with healthy controls. "
01/01/2011 - "While the NKG2D receptor has been described as the principal entity responsible for the lysis of several melanoma cell lines, the role of natural cytotoxicity receptors (NCRs) and DNAM-1 receptors in NK cell recognition and killing of melanoma cells has been recently emphasized. "
07/01/2008 - "This study analyzes the effects of acute social stress and different coping strategies employed in response to it on the development of B16F10 melanoma pulmonary metastases, the activation of the HPA axis and the NKG2D receptor expression. "
05/01/2015 - "The favorable effects of CEACAM1-3S related to enhanced immunogenicity, which was mediated by cell surface upregulation of NKG2D receptor ligands, thereby sensitizing melanoma cells to lysis by natural killer cells. "
10/13/2015 - "Interestingly, suboptimal cell death-inducing concentrations (1.5 μM αTOS/20 μM AA/0.2 μM VK3) effectively up-regulated activating Natural Killer (NK) cell ligands, including MICA (the stress-signaling ligand of the NKG2D receptor), and/or the ligands of at least one of the natural cytotoxicity receptors (NKp30, NKp44 and NKp46) in 5/6 melanoma cell lines. "
04/01/2011 - "This study was aimed to explore the difference of NK cell receptor NKG2D and NKG2A expression on NK cells and CD3(+) T cells and their ligand MHC-I A/B (major histocompatibility complex class I-related chains A/B) and HLA-E expression in leukemia cells, as well as its immunological significance. "
05/28/2015 - "The killing of human leukemia lymphoblasts by NK cells depended on the expression of the NKG2D receptor. "
01/01/2015 - "Human leukemia K562, OUN-1, HL-60, U937, K562/AO2 cell lines and primary leukemic cells were used to detect the NKG2D ligands (NKG2DL) expression such as MICA/B, ULBP-1, ULBP-2, ULBP-3, and NK cells receptor NKG2D, CD158a, CD158b were detected by flow cytometry. "
|1.||interleukin-21 (interleukin 21)
|4.||Carrier Proteins (Binding Protein)
|6.||Transforming Growth Factor beta1 (TGF beta 1)
|7.||C-Type Lectins (C-Type Lectin)
|9.||Transforming Growth Factor beta (TGF-beta)
|10.||Proteins (Proteins, Gene)
|4.||Transplantation (Transplant Recipients)