HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Acid Ceramidase

A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.
Networked: 82 relevant articles (4 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Liu, Xiang: 12 articles (12/2014 - 08/2006)
2. Hannun, Yusuf A: 10 articles (12/2014 - 08/2006)
3. Norris, James S: 10 articles (10/2013 - 08/2006)
4. Bielawska, Alicja: 9 articles (12/2014 - 03/2004)
5. Levade, Thierry: 8 articles (01/2014 - 04/2007)
6. Casas, Josefina: 7 articles (06/2013 - 04/2007)
7. Schuchman, Edward H: 6 articles (09/2014 - 02/2002)
8. Cheng, Joseph C: 6 articles (10/2013 - 08/2006)
9. Turner, Lorianne S: 6 articles (11/2012 - 09/2007)
10. Elojeimy, Saeed: 6 articles (12/2009 - 08/2006)

Related Diseases

1. Prostatic Neoplasms (Prostate Cancer)
2. Farber Lipogranulomatosis
3. Breast Neoplasms (Breast Cancer)
4. Noninfiltrating Intraductal Carcinoma (DCIS)
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Fenretinide
2. docetaxel (Taxotere)
3. N-lauroylsphingosine
4. oleoylsphingosine
5. Ceramidases
6. Sphingosine
7. Enzymes
8. Ceramides
9. Small Interfering RNA (siRNA)
10. Alkaline Ceramidase

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Heterologous Transplantation (Xenotransplantation)
3. Drug Therapy (Chemotherapy)