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X-Linked Bulbo-Spinal Atrophy (Syndrome, Kennedy)

An X-linked recessive form of spinal muscular atrophy. It is due to a mutation of the gene encoding the ANDROGEN RECEPTOR.
Also Known As:
Syndrome, Kennedy; Bulbo-Spinal Atrophy, X-Linked; Bulbospinal Muscular Atrophy, X-linked; Kennedy Disease; Kennedy Spinal and Bulbar Muscular Atrophy; Spinal And Bulbar Muscular Atrophy, X-Linked 1; Spinal and Bulbar Muscular Atrophy; X-linked Bulbospinal Muscular Atrophy; Atrophies, X-Linked Bulbo-Spinal; Atrophy, X-Linked Bulbo-Spinal; Bulbo Spinal Atrophy, X Linked; Bulbo-Spinal Atrophies, X-Linked; Bulbospinal Muscular Atrophy, X linked; Disease, Kennedy; Spinal And Bulbar Muscular Atrophy, X Linked 1; X Linked Bulbo Spinal Atrophy; X linked Bulbospinal Muscular Atrophy; X-Linked Bulbo-Spinal Atrophies; Kennedy Syndrome
Networked: 282 relevant articles (8 outcomes, 20 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Disease Progression
2. Motor Neuron Disease (Primary Lateral Sclerosis)
3. Neurodegenerative Diseases (Neurodegenerative Disease)
4. Prostatic Neoplasms (Prostate Cancer)
5. Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)

Experts

1. Sobue, Gen: 58 articles (12/2015 - 08/2002)
2. Katsuno, Masahisa: 49 articles (12/2015 - 08/2002)
3. Adachi, Hiroaki: 35 articles (12/2015 - 08/2002)
4. Tanaka, Fumiaki: 34 articles (11/2014 - 06/2004)
5. Suzuki, Keisuke: 22 articles (11/2015 - 03/2006)
6. Banno, Haruhiko: 21 articles (11/2012 - 03/2006)
7. Lieberman, Andrew P: 19 articles (01/2015 - 05/2004)
8. Minamiyama, Makoto: 18 articles (07/2013 - 03/2003)
9. Merry, Diane E: 15 articles (12/2015 - 01/2002)
10. Fischbeck, Kenneth H: 14 articles (11/2015 - 05/2005)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to X-Linked Bulbo-Spinal Atrophy:
1. Androgen Receptors (Androgen Receptor)IBA
2. polyglutamineIBA
3. Carbon MonoxideIBA
4. HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA
5. SodiumIBA
6. Butyrates (Butyrate)IBA
7. Leuprolide (Lupron)FDA LinkGeneric
8. Glutamine (L-Glutamine)FDA Link
9. Testosterone (Sustanon)FDA Link
10. Protons (Proton)IBA

Therapies and Procedures

1. Denervation
2. Molecular Targeted Therapy
3. Therapeutics
4. Castration