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Connective Tissue Growth Factor

A CCN protein family member that regulates a variety of extracellular functions including CELL ADHESION; CELL MIGRATION; and EXTRACELLULAR MATRIX synthesis. It is found in hypertrophic CHONDROCYTES where it may play a role in CHONDROGENESIS and endochondral ossification.
Also Known As:
CCN2 Protein; Hypertrophic Chondrocyte-Specific Protein 24; IGF-Binding Protein-Related Protein-2; IGFBP-8; IGFBP-rP2; Insulin-Like Growth Factor Binding Protein 8; Hypertrophic Chondrocyte Specific Protein 24; IGF Binding Protein Related Protein 2; Insulin Like Growth Factor Binding Protein 8
Networked: 1740 relevant articles (34 outcomes, 156 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Goldschmeding, Roel: 44 articles (12/2021 - 03/2001)
2. Leask, Andrew: 35 articles (01/2020 - 01/2002)
3. Nguyen, Tri Q: 22 articles (12/2021 - 01/2006)
4. Brigstock, David R: 22 articles (01/2018 - 01/2002)
5. Takigawa, Masaharu: 18 articles (01/2017 - 05/2002)
6. Lipson, Kenneth E: 15 articles (01/2022 - 12/2011)
7. Schultz, Gregory S: 14 articles (01/2017 - 09/2002)
8. Lin, Chien-Huang: 13 articles (10/2021 - 01/2011)
9. Kubota, Satoshi: 13 articles (01/2017 - 05/2002)
10. Oliver, Noelynn: 13 articles (07/2011 - 03/2004)

Related Diseases

1. Fibrosis (Cirrhosis)
2. Diabetic Nephropathies (Diabetic Nephropathy)
3. Inflammation (Inflammations)
4. Cicatrix (Scar)
5. Hypertrophy

Related Drugs and Biologics

1. Transforming Growth Factors (Transforming Growth Factor)
2. Collagen
3. Proteins (Proteins, Gene)
4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
5. Fibronectins (Fibronectin)
6. Collagen Type I (Type I Collagen)
7. Transforming Growth Factor beta1 (TGF beta 1)
8. Monoclonal Antibodies
9. Streptozocin (Streptozotocin)
10. Transforming Growth Factor beta (TGF-beta)

Related Therapies and Procedures

1. Trabeculectomy (Trabeculoplasty)
2. Therapeutics
3. Filtering Surgery
4. Ligation
5. Radiotherapy