Bone Morphogenetic Protein 3

A bone morphogenetic protein that is found at high concentrations in a purified osteoinductive protein fraction from BONE. Bone morphogenetic protein 3 is referred to as osteogenin, however it may play a role in variety of developmental processes.

Also Known As:

Networked: 16 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kerachian, Mohammad Amin: 2 articles (01/2018 - 07/2017)
2.	Ahlquist, David A: 2 articles (08/2013 - 12/2007)
3.	Shire, Abdirashid M: 2 articles (08/2013 - 12/2007)
4.	Zou, Hongzhi: 2 articles (08/2013 - 12/2007)
5.	Rokni, Parisa: 1 article (01/2018)
6.	Sakhinia, Ebrahim: 1 article (01/2018)
7.	Shariatpanahi, Afsaneh Mojtabanezhad: 1 article (01/2018)
8.	Chen, Rongchang: 1 article (10/2017)
9.	Fan, Lichao: 1 article (10/2017)
10.	Fang, Xia: 1 article (10/2017)

Related Diseases

1.	Uremia 08/01/2008 - "qPCR results confirmed the sense of expression change found in the arrays for insulin-like growth factor I, insulin-like growth factor II, collagen V alpha 1, bone morphogenetic protein 3 and proteoglycan type II. This study shows for the first time the profile of growth plate gene expression modifications caused by GH treatment in experimental uremia and provides a basis to further investigate selected individual genes with potential implication in the stimulating effect on the growth of GH treatment in chronic renal failure."
2.	Periodontal Diseases (Periodontal Disease) 12/01/1990 - "The potential for osteogenin in regenerating alveolar bone lost due to periodontal disease is suggested by these studies."
3.	Chronic Kidney Failure (Chronic Renal Failure) 08/01/2008 - "qPCR results confirmed the sense of expression change found in the arrays for insulin-like growth factor I, insulin-like growth factor II, collagen V alpha 1, bone morphogenetic protein 3 and proteoglycan type II. This study shows for the first time the profile of growth plate gene expression modifications caused by GH treatment in experimental uremia and provides a basis to further investigate selected individual genes with potential implication in the stimulating effect on the growth of GH treatment in chronic renal failure."
4.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2018 - "Bone Morphogenetic Protein 3 (BMP3) was identified as a candidate tumor suppressor gene putatively down-regulated in colorectal cancer (CRC). " 07/01/2017 - "Assessment of Bone Morphogenetic Protein 3 Methylation in Iranian Patients with Colorectal Cancer." 12/01/2007 - "Four genes specifically methylated in colorectal cancer [bone morphogenetic protein 3 (BMP3), EYA2, aristaless-like homeobox-4 (ALX4), and vimentin] were selected from 41 candidate genes and evaluated on 74 cancers, 62 adenomas, and 70 normal epithelia. "
5.	Wounds and Injuries (Trauma) 11/01/1992 - "Baboon osteogenin induced complete regeneration of the cranial wound. " 11/01/1989 - "The partially purified protein (osteogenin) produced significantly more bone formation in calvarial wounds than was found in the untreated controls. "

Related Drugs and Biologics

1.	Proteoglycans (Proteoglycan)
2.	Insulin-Like Growth Factor II (Somatomedin A)
3.	Insulin-Like Growth Factor I (IGF-1)
4.	Collagen
5.	Long Noncoding RNA
6.	Toll-Like Receptor 9
7.	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)
8.	Intercellular Signaling Peptides and Proteins (Growth Factors)
9.	Bone Morphogenetic Proteins (Bone Morphogenetic Protein)
10.	Biomarkers (Surrogate Marker)