|1.||Rao, Jasti S: 27 articles (05/2014 - 01/2002)|
|2.||Gondi, Christopher S: 18 articles (06/2012 - 09/2003)|
|3.||Dinh, Dzung H: 18 articles (03/2012 - 01/2002)|
|4.||Ploug, Michael: 15 articles (12/2015 - 04/2004)|
|5.||Gujrati, Meena: 13 articles (01/2011 - 09/2003)|
|6.||Høyer-Hansen, Gunilla: 11 articles (11/2015 - 05/2004)|
|7.||Lakka, Sajani S: 11 articles (09/2010 - 01/2002)|
|8.||Mazar, Andrew P: 10 articles (06/2015 - 08/2002)|
|9.||Danø, Keld: 10 articles (08/2012 - 04/2002)|
|10.||Magdolen, Viktor: 10 articles (01/2011 - 01/2002)|
08/01/2009 - "The present study investigated the distribution of uPA and its receptor (uPAR) in EOC cell lines, primary and metastatic tumors, and the relationship between uPA/uPAR and matrix metalloproteinase (MMP) expression using immunohistochemistry. "
10/01/2012 - "MDSC accumulation is tumor burden-dependent, and tumor-derived factors such as uPA and its receptor uPAR play a role in their recruitment."
06/01/2012 - "Intervention with this proteolysis by targeting of uPA receptor (uPAR) has been proposed to represent a novel approach for inhibiting tumor progression. "
11/01/2009 - "Members of this system, including uPA and its receptor (uPAR), are overexpressed in several malignant tumors. "
11/01/2008 - "uPA and its receptor (uPAR) have been strongly implicated in tumor invasion, angiogenesis and progression. "
|2.||Breast Neoplasms (Breast Cancer)
03/12/1999 - "In this study, we characterized the effects of the VLDLr on the internalization, catabolism, and function of the uPA receptor (uPAR) in MCF-7 and MDA-MB-435 breast cancer cells. "
03/15/1996 - "The combined increased expression of uPA and its cellular receptor, uPAR on the surface of tumor epithelial cells may account for the activation of the proteolytic system which occurs in breast cancer."
01/01/2013 - "The purpose of this study was to assess the concentration of urokinase-type plasminogen activator receptor (uPAR) in the serum of 103 women with breast cancer. "
05/20/2009 - "This study describes the synthesis and preliminary biologic evaluation of an (111)In-labeled peptide antagonist of the urokinase-type plasminogen activator receptor (uPAR) as a potential probe for assessing metastatic potential of human breast cancer in vivo. "
02/01/2000 - "In the present study involving 2780 patients with primary invasive breast cancer, we have evaluated the prognostic importance of the four major components of the uPA system [uPA, the receptor uPAR (CD87), and the inhibitors PAI-1 and PAI-2]. "
|3.||Neoplasm Metastasis (Metastasis)
06/01/2015 - "uPA and the receptor uPAR, are overexpressed in a number of malignant tumours and uPA/uPAR play major roles in adhesion, migration, invasion and metastasis of cancer cells. "
12/01/2010 - "Its association with cell surfaces through the uPA receptor (uPAR) is central to its function and plays an important role in cancer invasion and metastasis. "
08/15/2008 - "Directional and controllable degradation of extracellular matrix mediated by the uPA-uPA receptor (uPAR) system is ubiquitously implicated in tumor establishment, invasion and metastasis. "
01/01/1993 - "Colonic carcinomas and liver metastases contained higher levels of free u-PA receptor compared to their corresponding normal tissues. "
01/01/2013 - "Urokinase (uPA) and its receptor (uPAR) play an important role in tumour growth and metastasis, and overexpression of these molecules is strongly correlated with poor prognosis in a variety of malignant tumours. "
07/15/2007 - "The purpose of this study was to evaluate the therapeutic potential of using plasmid-expressed RNA interference (RNAi) targeting urokinase-type plasminogen activator (uPA) receptor (uPAR) and uPA to treat human glioma. "
01/03/2002 - "Our previous studies showed that the urokinase-type plasminogen activator receptor (uPAR) and the p16 tumor suppressor gene play a significant role in glioma invasion. "
01/01/2000 - "In this study, we determined if the urokinase-type plasminogen activator (uPA) and/or the urokinase-type plasminogen activator receptor (uPAR) were responsible for the invasion activity of a human glioma cell line. "
05/25/2000 - "The distribution of the urokinase-type plasminogen activator receptor (uPAR) on human glioma cells was examined as a function of culture conditions, using immunofluorescence and immunophotoelectron microscopy. "
07/01/1997 - "Our previous studies showed that glioblastomas express increased urokinase-type plasminogen activator receptors (uPARs) in comparison to low-grade gliomas (Yamamoto et al., Cancer Res., 54, 5016-5020, 1994). "
|5.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
02/01/2006 - "To study the expressions and clinical significance of urokinase-type plasminogen activator (uPA) and uPA receptor (uPAR) in tongue squamous cell carcinoma (TSCC). "
06/01/2005 - "To study the expressions and clinical significance of urokinase-type plasminogen activator (uPA) and uPA receptor (uPAR) in laryngeal squamous cell carcinoma (LSCC). "
11/01/2008 - "To investigate the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in squamous cell carcinoma of hypopharynx and reveal the correlation of the major clinicopathological parameters and prognosis. "
10/15/2007 - "Urinary-type plasminogen activator (uPA) and its receptor (uPAR) in squamous cell carcinoma of the oral cavity."
02/01/2006 - "[Expressions and clinical significance of urokinase-type plasminogen activator (uPA) and uPA receptor (uPAR) in tongue squamous cell carcinoma]."
|1.||Urokinase-Type Plasminogen Activator (Urokinase)
|2.||Protease Inhibitors (Protease Inhibitor)
|3.||Plasminogen Activators (Plasminogen Activator)
|4.||Plasminogen Activator Inhibitor 1
|6.||Messenger RNA (mRNA)
|7.||Tissue Plasminogen Activator (Alteplase)
|8.||Matrix Metalloproteinase 9 (Gelatinase B)
|9.||Proteins (Proteins, Gene)
|1.||Heterologous Transplantation (Xenotransplantation)
|3.||Negative-Pressure Wound Therapy