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Mucin-3

A membrane-bound mucin subtype that is primarily found in INTESTINAL MUCOSA. Two closely-related subtypes of this protein have been identified in humans.
Also Known As:
Mucin 3; Mucin 3A; Mucin 3B; Mucin-3A; Mucin-3B
Networked: 107 relevant articles (2 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Chen, Guojiang: 5 articles (01/2018 - 02/2010)
2. Feng, Jiannan: 5 articles (01/2018 - 02/2010)
3. Han, Gencheng: 5 articles (01/2018 - 02/2010)
4. Shen, Beifen: 5 articles (01/2018 - 02/2010)
5. Wang, Renxi: 5 articles (01/2018 - 02/2010)
6. Hou, Chunmei: 4 articles (01/2018 - 12/2012)
7. Xiao, He: 4 articles (01/2018 - 12/2012)
8. Li, Yan: 4 articles (01/2017 - 02/2010)
9. Kikushige, Yoshikane: 4 articles (09/2015 - 12/2010)
10. Jiang, Xingwei: 3 articles (01/2018 - 12/2012)

Related Diseases

1. Neoplasms (Cancer)
06/01/2018 - "We described schematically 4 types of patterns depending on predominant growth pattern, except one case: 1) Large-sized solid cohesive groups (6 cases), 2) Small- to medium-sized solid cohesive groups with trabeculae/ribbons and glandular structures (6 cases), 3) Mixed growth patterns (20 cases), 4) Invasive tumor with prominent extracellular and/or intracellular mucin (3 cases). "
01/01/1989 - "While typical of pure MC, abundant mucin (3+/3+) was noted in smears from three cases of mixed tumor and is thus necessary but not sufficient for a diagnosis of pure MC. "
05/01/2009 - "Histological sections from 12 adenocarcinomas were selected when the following materials were predominantly found in the neoplastic glands with pores at the invading tumor edge: mucin (3 cases, group I), neutrophilic granulocyes (3 cases, group II), necrotic material (3 cases, group III) and invaginated stroma (3 cases, group IV). "
01/01/2023 - "However, some ICRs have been reported to be expressed on both T-cells and tumor cells, including V-domain immunoglobulin suppressor of T cell activation (VISTA), Galectin-9, and T-cell immunoglobulin mucin-3 (TIM-3). "
01/01/2022 - "We used multiplexed quantitative immunofluorescence panels to determine the association of major TILs subpopulations, CD8+ cytotoxic T cells, CD4+ helper T cells and CD20+ B cells, and T cell exhaustion markers, programmed cell death protein-1 (PD-1),lymphocyte-activation gene 3 (LAG-3) and T cell immunoglobulin mucin-3 (TIM-3) with outcomes in a multi-institutional cohort of baseline tumor samples from 179 patients with NSCLC treated with ICI. "
2. Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
3. Colitis
4. Body Weight (Weight, Body)
5. Bites and Stings (Sting)

Related Drugs and Biologics

1. Immunoglobulins (Immunoglobulin)
2. Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)
3. Antigens
4. Cyclin D
5. Interleukin-1beta (Interleukin 1 beta)
6. Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
7. Cyclooxygenase 2 (Cyclooxygenase-2)
8. Cyclin-Dependent Kinases (cdk Proteins)
9. Oligosaccharides
10. Kynurenine

Related Therapies and Procedures

1. Immunotherapy
2. Therapeutics
3. Aftercare (After-Treatment)