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Malignant Atrophic Papulosis

Variously described as a vasculopathy, endovasculitis, or occlusive arteriopathy, this condition occurs in a benign cutaneous form and a lethal multiorgan systemic variant. It is characterized by a narrowing and occlusion of the lumen of small to medium-sized blood vessels, leading to ischemia and infarction in the involved organ systems. The etiology and pathophysiology are unknown.
Also Known As:
Degos Syndrome; Degos's Malignant Atrophic Papulosis; Erythrokeratoderma en cocardes; Atrophic Papuloses, Malignant; Atrophic Papulosis, Malignant; Disease, Degos; Disease, Kohlmeier-Degos; Kohlmeier Degos Disease; Malignant Atrophic Papuloses; Papuloses, Malignant Atrophic; Papulosis, Malignant Atrophic; Syndrome, Degos; Degos Disease; Kohlmeier-Degos Disease
Networked: 96 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Malignant Atrophic Papulosis
2. Cicatrix (Scar)
3. Hyperpigmentation
4. Pyoderma Gangrenosum
5. Vasculitis (Vasculitides)

Experts

1. Magro, Cynthia M: 4 articles (01/2015 - 11/2002)
2. Hanneken, Sandra: 3 articles (01/2014 - 03/2006)
3. Betz, Regina C: 3 articles (01/2014 - 03/2006)
4. Kruse, Roland: 3 articles (01/2014 - 03/2006)
5. Shapiro, Lee: 2 articles (01/2015 - 04/2011)
6. El Shabrawi-Caelen, Laila: 2 articles (01/2014 - 12/2004)
7. Pasternack, Sandra M: 2 articles (01/2014 - 03/2006)
8. Yu, Hong: 2 articles (01/2014 - 06/2013)
9. Scheinfeld, Noah: 2 articles (06/2013 - 01/2011)
10. Shapiro, Lee S: 2 articles (01/2013 - 01/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Malignant Atrophic Papulosis:
1. eculizumabFDA Link
2. treprostinilFDA Link
3. AntibodiesIBA
4. RetinoidsIBA
5. Dichlorodiphenyldichloroethane (DDD)IBA
6. Dental Porcelain (Porcelain)IBA
7. Keratin-5 (Keratin 5)IBA
8. Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA
9. Immunoglobulins (Immunoglobulin)IBA
10. Aspirin (Acetylsalicylic Acid)FDA LinkGeneric

Therapies and Procedures

1. Solid-State Lasers
2. Laparotomy
3. Transplants (Transplant)
4. Radiotherapy
5. PUVA Therapy