Cellular Retinol-Binding Proteins

A subclass of retinol-binding proteins that take part in the intracellular storage and transport of RETINOL. They are both functionally and structurally distinct from PLASMA RETINOL-BINDING PROTEINS.
Also Known As:
Retinol-Binding Proteins, Cellular; Cellular Retinol Binding Protein; Cellular Retinol-Binding Protein I; Retinol Binding Protein 2; Retinol-Binding Protein (Type 2); Retinol-Binding Protein 1; Retinol-Binding Protein 1, Cellular; Retinol-Binding Protein 2, Cellular; Retinol-Binding Protein II, Cellular; Cellular Retinol Binding Protein I; Retinol Binding Protein 1; Retinol Binding Protein 1, Cellular; Retinol Binding Protein 2, Cellular; Retinol Binding Protein II, Cellular; Retinol Binding Proteins, Cellular
Networked: 66 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results


1. Salcedo, Mauricio: 3 articles (01/2013 - 06/2010)
2. Peralta, Raúl: 3 articles (01/2013 - 06/2010)
3. Valdivia, Alejandra: 3 articles (01/2013 - 06/2010)
4. Pierzchalski, Keely: 2 articles (10/2014 - 05/2013)
5. Kane, Maureen A: 2 articles (10/2014 - 05/2013)
6. Paniagua, Lucero: 2 articles (01/2013 - 01/2012)
7. Romero, Pablo: 2 articles (01/2013 - 01/2012)
8. Gallegos, Francisco: 2 articles (01/2012 - 06/2010)
9. Mira-y-Lopez, Rafael: 2 articles (02/2005 - 04/2004)
10. Farias, Eduardo F: 2 articles (02/2005 - 01/2005)

Related Diseases

1. Squamous Cell Carcinoma (Epidermoid Carcinoma)
2. Carcinoma (Carcinomatosis)
3. Osteosarcoma (Osteogenic Sarcoma)
4. Neoplasms (Cancer)
5. Vitamin A Deficiency
03/01/1987 - "The demonstration of proper vitamin A storage in treated children as well as normal levels of cellular retinol-binding protein suggest the vitamin A deficiency frequently observed in children with biliary atresia may be due primarily to faulty absorption rather than a combination of poor absorption and impaired hepatic vitamin A metabolism."
01/01/1998 - "We have previously reported that the induction of Vitamin A deficiency results in a threefold decrease in the hepatic expression of cellular retinol binding protein I (CRBP I) mRNA in vivo and that the treatment of intestinal cell lines in vitro with retinoids leads to the induction of CRBP I transcription. "
01/01/1987 - "We studied the effects of vitamin A deficiency and repletion on rat insulin release and islet cellular retinol binding protein (CRBP) and cellular retinoic acid binding protein (CRABP). "
02/26/1991 - "Two different metabolic alterations in vitamin A status are known to cause changes in the amount of circulating retinol-binding protein (RBP) and cellular retinol-binding protein (CRBP) in experimental animals; namely vitamin A deficiency, characterized by depleted retinol-liver stores and hypervitaminosis A, characterized by hepatic accumulation of retinyl esters. "
02/01/2001 - "These results show that: RALDH1 and RALDH2 have distinct mRNA expression patterns in multiple cell types in three vitamin A target tissues; RALDH expression occurs in cell types that express cellular retinol-binding protein and retinol dehydrogenase isozymes (except stellate cells, for which retinol dehydrogenase expression remains unknown); vitamin A deficiency and RA supplementation affects the loci and intensity of RALDH mRNAs in testis; and low-dose RA does not substitute completely for retinol. "

Related Drugs and Biologics

1. cellular retinoic acid binding protein I
2. cellular retinoic acid binding protein II
3. Vitamin A (Retinol)
4. Carrier Proteins (Binding Protein)
5. Tretinoin (Retinoic Acid)
6. Sucrose (Saccharose)
7. Proteins (Proteins, Gene)
8. Retinoic Acid Receptors (Retinoic Acid Receptor)
9. Messenger RNA (mRNA)
10. Retinol-Binding Proteins (Retinoid Binding Proteins)