|1.||Zwierz, Krzysztof: 7 articles (01/2014 - 03/2008)|
|2.||Waszkiewicz, Napoleon: 5 articles (01/2014 - 01/2011)|
|3.||Kępka, Alina: 4 articles (01/2014 - 01/2011)|
|4.||Szajda, Sławomir Dariusz: 4 articles (01/2014 - 09/2009)|
|5.||Chojnowska, Sylwia: 3 articles (01/2014 - 09/2010)|
|6.||Zalewska-Szajda, Beata: 3 articles (01/2014 - 01/2012)|
|7.||Tutor, J Carlos: 3 articles (09/2005 - 01/2003)|
|8.||Casal, J Antonio: 3 articles (09/2005 - 01/2003)|
|9.||Ładny, Jerzy Robert: 2 articles (01/2014 - 01/2013)|
|10.||Zalewska, Anna: 2 articles (09/2013 - 01/2013)|
|1.||Alcoholism (Alcohol Abuse)
04/01/1995 - "In the present study, we have compared "Hex B" with CDT as markers of alcohol abuse in a group of alcoholics hospitalized for detoxification after a period of heavy alcohol abuse. "
11/01/1997 - "We suggest that serum beta-Hex B% can be a useful and inexpensive laboratory test for alcohol abuse."
04/01/1995 - "The possible reasons for a relation between these two markers are discussed, and it is concluded that more experience of both "Hex B" and CDT in unselected populations is needed to establish the diagnostic potential of these tests as markers of alcohol abuse."
06/01/1994 - "Since Hex B is a sensitive marker for alcohol abuse, we also investigated its serum level in subjects that could be suspected of alcohol abuse. "
06/01/1991 - "It is concluded that Hex "B" is a useful marker for alcohol abuse."
10/01/1983 - "These findings indicate that the formation of mixed disulfide bonds in the tumor Hex B increases the net negative charge and results in the appearance of a heat-labile form."
10/01/1983 - "With respect to heat stability, Hex B from the normal lung was very stable at 52 degrees, while the tumor Hex B (mixture of pI 7.6 and 7.9 forms) was unstable. "
09/30/2010 - "The considerably higher activity of HEX, HEX-A, GLU, GAL, MAN, FUC and descending trend of activity of HEX-B were noticed in saliva of patients with salivary gland tumors in comparison to healthy volunteers. "
09/30/2010 - "In salivary gland tumor tissue the activity of HEX, HEX-A, HEX-B, GAL, FUC was considerably higher than in comparison to healthy salivary gland tissue and ascending trend of activity of GLU, MAN was also noticed. "
09/30/2010 - "The aim of the presented study was an the assessment of the activity of HEX, with its isoforms HEX-A and HEX-B, GLU, GAL, MAN and FUC in salivary gland tumor tissues in comparison to a healthy salivary gland tissues taken during autopsy. "
|3.||Sandhoff Disease (Sandhoff's Disease)
10/01/1997 - "Hex B (beta beta homodimer) is also defective in Sandhoff disease. "
09/01/1993 - "This phenomenon was also not seen in assays of leukocytes from carriers for Sandhoff disease, a condition associated with a reduction in the amount of hex B. "
03/01/1994 - "Diarrhea and autonomic dysfunction in a patient with hexosaminidase B deficiency (Sandhoff disease)."
02/16/1973 - "Hexosaminidase-A and hexosaminidase-B: studies in Tay-Sachs' and Sandhoff's disease."
01/01/2007 - "Asseys of hexosaminidase A and hexosaminidase B showed low activities, and we found a membranous cytoplasmic body in the submucosal nerve, leading to the diagnosis of Sandhoff disease. "
02/01/1996 - "However, the Hex B isoenzyme from carcinoma patients exhibited some characteristic variations in pH, temperature, substrate concentration optima, and isoelectric point compared with the control. "
02/01/1996 - "From these observations it may be inferred that altered properties of the Hex B isoenzyme fraction from carcinoma patients may be the reason for the elevated activity of hexosaminidase in carcinoma of the uterine cervix."
02/01/1996 - "Hex A was found to be the major isoenzyme in control tissues, whereas Hex B was the major isoenzyme in carcinoma tissues. "
10/01/1983 - "Activities of beta-hexosaminidase A and beta-hexosaminidase B (Hex B) were measured both in human lung carcinoma and the adjacent normal tissues of 47 patients. "
05/01/1979 - "Hex A and Hex B of renal carcinoma tissue differed from each other in physicochemical properties such as pH dependence of enzyme activity, thermostability, and Km's for two synthetic substrates, but each isozyme maintained its same physicochemical properties whether from normal or from carcinoma tissue. "
|5.||Colonic Neoplasms (Colon Cancer)
05/01/2001 - "GINI was tested on colon cancer and Sandhoff disease cell lines, which contained previously characterized nonsense mutations in the MutL homolog 1 (MLH1) and hexosaminidase B (HEXB) genes, respectively. "
10/01/1984 - "In view of the reported low levels of colon cancer among Seventh-day Adventists (SDA) we determined levels of total HEX, and its heat-labile (HEX-A) and heat-stable (HEX-B) isozymes in vegetarian SDA, lacto-ovo vegetarian SDA, nonvegetarian SDA, and the general public. "
09/01/2009 - "We observe a significant increase in the activity of HEX, HEX A and HEX B expressed in pKat/mg of creatinine was found in urine of patients bearing tumor of diameter 6.0-7.0 cm in comparison to patients with tumor of diameter 4.0-5.0 cm. The present study results suggest that determination of HEX, HEX A and HEX B activity in blood serum and urine may be used to detect colon cancer in its early stages. "
|1.||Hexosaminidase A (Hex A)
|3.||Protein Isoforms (Isoforms)
|4.||Glycoside Hydrolases (Endoglycosidases)