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Ribosome Inactivating Proteins

N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.
Also Known As:
Polynucleotide Adenosine Glycosidase; RIP (Ribosome Inactivating Proteins); RNA Glycosylase; rRNA N-Glycosylases; Adenosine Glycosidase, Polynucleotide; Glycosidase, Polynucleotide Adenosine; Glycosylase, RNA; Inactivating Proteins, Ribosome; N-Glycosidase, RNA; N-Glycosylases, rRNA; Proteins, Ribosome Inactivating; RNA N Glycosidase; rRNA N Glycosylases; RNA N-Glycosidase
Networked: 32 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Melzig, Matthias F: 2 articles (01/2014 - 10/2013)
2. Meng, Yao: 1 article (05/2015)
3. Meng, Yanfa: 1 article (05/2015)
4. He, Lingli: 1 article (05/2015)
5. Li, Gangrui: 1 article (05/2015)
6. Li, Linli: 1 article (05/2015)
7. Fan, Xiang: 1 article (05/2015)
8. Verma, H N: 1 article (03/2015)
9. Prasad, Vivek: 1 article (03/2015)
10. Srivastava, Aparana: 1 article (03/2015)

Related Diseases

1. Neoplasms (Cancer)
2. Carcinoma (Carcinomatosis)
3. Infection
4. Hepatocellular Carcinoma (Hepatoma)
5. Choriocarcinoma

Related Drugs and Biologics

1. Immunotoxins (Immunotoxin)
2. Shiga Toxins (Vero Toxin)
3. Ricin
4. Peptide Elongation Factor 2 (EF-2)
5. Immunoconjugates (Immunoconjugate)
6. Complementary DNA (cDNA)
7. Bispecific Antibodies
8. Thymidine
9. Saponins
10. Ribosomal RNA

Related Therapies and Procedures

1. Immunotherapy