A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA.
Also Known As:
A-Kinase Anchor Proteins; Protein Kinase A Anchor Proteins; A Kinase Anchoring Protein; A Kinase Anchoring Proteins; Anchor Proteins, A-Kinase; Anchoring Protein, A-Kinase; Protein, A-Kinase Anchoring; A-Kinase Anchoring Protein; A-Kinase Anchoring Proteins