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Langerhans Cell Sarcoma

Rare malignant neoplasm of dendritic LANGERHANS CELLS exhibiting atypical cytology, frequent mitoses, and aggressive clinical behavior. They can be distinguished from other histiocytic and dendritic proliferations by immunohistochemical and ultrastructure studies. Cytologically benign proliferations of Langerhans cells are called LANGERHANS CELL HISTIOCYTOSIS.
Also Known As:
Langerhans Cell Sarcomas; Sarcoma, Langerhans Cell; Sarcomas, Langerhans Cell
Networked: 14 relevant articles (0 outcomes, 3 trials/studies)

Disease Context: Research Results

Related Diseases

1. Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
2. Hairy Cell Leukemia
3. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
4. Neoplasms (Cancer)
5. Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell)

Experts

1. Sanik, Eugene: 1 article (11/2015)
2. Susa, Joseph: 1 article (11/2015)
3. Karai, Laszlo J: 1 article (11/2015)
4. Ricotti, Carlos A: 1 article (11/2015)
5. Aleodor, Andea A: 1 article (11/2015)
6. Sinkre, Prasanna: 1 article (11/2015)
7. Wen, Mei-Chin: 1 article (08/2014)
8. Chang, Nien-Yi: 1 article (08/2014)
9. Lee, Fang-Yi: 1 article (08/2014)
10. Wang, John: 1 article (08/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Langerhans Cell Sarcoma:
1. DNA (Deoxyribonucleic Acid)IBA
2. Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
3. Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA
4. S100 Proteins (S 100 Protein)IBA
5. CladribineFDA LinkGeneric
6. Proteins (Proteins, Gene)IBA
7. AntigensIBA
8. DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA
9. imatinib (Gleevec)FDA Link
10. fascinIBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Liver Transplantation
3. Transplantation (Transplant Recipients)
4. Radiotherapy