|1.||Frigo, Daniel E: 2 articles (05/2015 - 01/2011)|
|2.||Chung, Sung Hyun: 2 articles (03/2014 - 01/2014)|
|3.||Kim, Do Yeon: 2 articles (03/2014 - 01/2014)|
|4.||Jo, Hee Kyung: 2 articles (03/2014 - 01/2014)|
|5.||Jeong, Kyong Ju: 2 articles (03/2014 - 01/2014)|
|6.||Li, Jun: 2 articles (01/2014 - 09/2013)|
|7.||Liu, Lin: 2 articles (01/2014 - 09/2013)|
|8.||Schmitt, John M: 2 articles (05/2012 - 06/2004)|
|9.||Soderling, Thomas R: 2 articles (08/2011 - 06/2004)|
|10.||Tokumitsu, Hiroshi: 2 articles (04/2008 - 05/2002)|
01/15/2014 - "In summary, BA effectively ameliorates hyperglycemia through inhibition of hepatic gluconeogenesis via modulating the CAMKK-AMPK-CREB signaling pathway. "
03/01/2014 - "In summary, eugenol effectively ameliorates hyperglycemia through inhibition of hepatic gluconeogenesis via modulating CAMKK-AMPK-CREB signaling pathway. "
06/01/2013 - "Glyceollin improves endoplasmic reticulum stress-induced insulin resistance through CaMKK-AMPK pathway in L6 myotubes."
05/01/2008 - "RESULTS; We have made the following novel observations: 1) BBR dose-dependently inhibited respiration in L6 myotubes and muscle mitochondria, through a specific effect on respiratory complex I, similar to that observed with metformin and rosiglitazone; 2) activation of AMPK by BBR did not rely on the activity of either LKB1 or CAMKKbeta, consistent with major regulation at the level of the AMPK phosphatase; and 3) a novel BBR derivative, dhBBR, was identified that displayed improved in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents. "
01/01/2014 - "In this study, we examined stroke outcomes in ovariectomized CaMKK β and CaMK IV deficient females. "
01/01/2014 - "Therefore, CaMKK signaling may be a potential target for stroke treatment in both males and females."
01/01/2014 - "Inhibition of CaMKK signaling exacerbated stroke outcome and increased BBB impairment, transcriptional inactivation and inflammatory responses in females after stroke. "
01/01/2014 - "It has recently been suggested that CaMKK and CaMK IV, a downstream target molecule, are neuroprotective in stroke in males. "
09/01/2013 - "Our data demonstrated that pharmacological and genetic inhibition of CaMKK aggravated stroke injury. "
|4.||Prostatic Neoplasms (Prostate Cancer)
05/01/2012 - "Taken together these data suggest a survival role for CaM KK operating through AKT and BAD in LNCaP prostate cancer cells."
10/15/2015 - "Autocrine Activation of CHRM3 Promotes Prostate Cancer Growth and Castration Resistance via CaM/CaMKK-Mediated Phosphorylation of Akt."
12/01/2012 - "Down-regulation of calcium/calmodulin-dependent protein kinase kinase 2 by androgen deprivation induces castration-resistant prostate cancer."
05/01/2012 - "Our goals were to examine the mechanism of carbachol activation of AKT and BAD in LNCaP prostate cancer cells and evaluate whether CaM KK may be mediating carbachol's activation of AKT and cell survival. "
01/15/2011 - "CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells."
01/01/2015 - "Calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) was found to be 7-fold overexpressed in gastric tumor tissues. "
08/01/2011 - "Since tumor dissemination requires cell migration to ectopic sites, this CaMKK pathway may be a putative therapeutic target to limit medulloblastoma metastasis."
07/06/2011 - "This highlighted calcium/calmodulin-dependent protein kinase kinase 2, which we show is overexpressed in prostate cancer and regulates cancer cell growth via its unexpected role as a hormone-dependent modulator of anabolic metabolism. "
08/01/2015 - "Our data using liver kinase B1-deficient cancer cells suggest that proteasome inhibitor-induced AMPK activation is primarily mediated by Calcium/Calmodulin-dependent kinase kinase β (CaMKKβ). "
|1.||Electron Transport Complex I (NADH-CoQ Reductase)
|6.||Calmodulin (Calcium-Dependent Activator Protein)
|7.||Calcium-Calmodulin-Dependent Protein Kinase Kinase
|9.||Protein Kinases (Protein Kinase)
|10.||Proteins (Proteins, Gene)