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Elongation Factor 2 Kinase

A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEPTIDE ELONGATION FACTOR 2. The enzyme lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE, however it is regulated by phosphorylation by PROTEIN KINASE A and through intramolecular autophosphorylation.
Also Known As:
CAM Kinase III; Cam PK III; E-2 Kinase; EF-2 Kinase; Eukaryotic Elongation Factor-2 Kinase; Protein Kinase CPK3; eEF-2-Specific Ca and Calmodulin-Dependent Protein Kinase III; Calcium Calmodulin Dependent Protein Kinase Type 3; Calmodulin Dependent Protein Kinase III; E 2 Kinase; EF 2 Kinase; Eukaryotic Elongation Factor 2 Kinase; Kinase CPK3, Protein; Kinase, EF-2; eEF 2 Specific Ca and Calmodulin Dependent Protein Kinase III; Calcium-Calmodulin-Dependent Protein Kinase Type 3; Calmodulin-Dependent Protein Kinase III
Networked: 22 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Yang, Jin-Ming: 3 articles (02/2013 - 05/2002)
2. Tavares, Clint D J: 2 articles (01/2016 - 01/2012)
3. Dalby, Kevin N: 2 articles (01/2016 - 01/2012)
4. Werner, Jörn M: 2 articles (05/2015 - 05/2015)
5. Mikolajek, Halina: 2 articles (05/2015 - 05/2015)
6. Proud, Christopher G: 2 articles (05/2015 - 05/2015)
7. Arora, Sonia: 2 articles (10/2003 - 05/2002)
8. Cho, Eun Jeong: 1 article (01/2016)
9. Devkota, Ashwini K: 1 article (01/2016)
10. Wang, Gen-zhu: 1 article (07/2015)

Related Diseases

1. Glioma (Gliomas)
2. Neoplasms (Cancer)
3. Breast Neoplasms (Breast Cancer)
4. Anoxia (Hypoxia)
5. Atherosclerotic Plaque (Atheroma)

Related Drugs and Biologics

1. Elongation Factor 2 Kinase
2. Peptide Elongation Factor 2 (EF-2)
3. Intercellular Signaling Peptides and Proteins (Growth Factors)
4. Protein Kinases (Protein Kinase)
5. Proline (L-Proline)
6. Phosphotransferases (Kinase)
7. Peptide Elongation Factors (Elongation Factor)
8. Mitogens
9. Doxorubicin (Adriamycin)
10. Antibodies