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Echinocandins

Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS.
Also Known As:
Aculeacins; Mulundocandins; Pneumocandins; Aculeacin; Echinocandin; Pneumocandin
Networked: 1077 relevant articles (132 outcomes, 106 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Walsh, Thomas J: 33 articles (01/2022 - 01/2002)
2. Perlin, David S: 30 articles (02/2021 - 04/2006)
3. Kontoyiannis, Dimitrios P: 19 articles (12/2020 - 12/2003)
4. Wiederhold, Nathan P: 18 articles (10/2019 - 12/2007)
5. Roilides, Emmanuel: 17 articles (02/2022 - 07/2007)
6. Lewis, Russell E: 14 articles (12/2020 - 05/2008)
7. Patterson, Thomas F: 14 articles (10/2019 - 09/2006)
8. Muñoz, Patricia: 13 articles (01/2021 - 08/2014)
9. Castanheira, Mariana: 12 articles (11/2022 - 01/2011)
10. Pfaller, Michael A: 11 articles (11/2022 - 01/2011)

Related Diseases

1. Invasive Candidiasis
2. Aspergillosis
3. Infections
4. Candidiasis (Moniliasis)
5. Candidemia

Related Drugs and Biologics

1. Caspofungin (Cancidas)
2. Anidulafungin
3. Azoles
4. Antifungal Agents
5. Fluconazole (Zonal)
6. Micafungin (FK463)
7. Amphotericin B (Amphotericin)
8. Triazoles
9. Voriconazole (Vfend)
10. Polyenes

Related Therapies and Procedures

1. Therapeutics
2. Salvage Therapy
3. Hematopoietic Stem Cell Transplantation
4. Critical Care (Surgical Intensive Care)
5. Catheters