|1.||Yanagita, Ryo C: 2 articles (06/2012 - 01/2012)|
|2.||Suzuki, Nobutaka: 2 articles (06/2012 - 01/2012)|
|3.||Irie, Kazuhiro: 2 articles (06/2012 - 01/2012)|
|4.||Tokuda, Harukuni: 2 articles (06/2012 - 01/2012)|
|5.||Suenaga, Kiyotake: 1 article (06/2012)|
|6.||Kikumori, Masayuki: 1 article (06/2012)|
|7.||Nagai, Hiroshi: 1 article (06/2012)|
|8.||Fujiwara, Takeshi: 1 article (01/2012)|
|9.||Murakami, Kazuma: 1 article (01/2012)|
|10.||Murakami, Akira: 1 article (01/2012)|
|1.||Melanoma (Melanoma, Malignant)
05/01/1996 - "In the present study, we explore the mechanism by which the bryostatins inhibit growth to B16/F10 mouse melanoma cells in vitro. "
05/01/1996 - "The bryostatins inhibit growth of B16/F10 melanoma cells in vitro through a protein kinase C-independent mechanism: dissociation of activities using 26-epi-bryostatin 1."
06/14/2012 - "These results suggest that 5 is a potent PKC ligand without tumor-promoting activity and could be a therapeutic lead for the treatment of cancer, like bryostatins."
08/01/2004 - "sertula" has been implicated as the source of the bryostatins, polyketides that provide chemical defense to the host and are also being tested for use in human cancer treatments. "
09/01/1999 - "The bryostatins are a unique family of cancer chemotherapeutic candidates isolated from marine bryozoa. "
06/09/1998 - "Like bryostatin, acetal 7c exhibited significant levels of in vitro growth inhibitory activity (1.8-170 ng/ml) against several human cancer cell lines, providing an important step toward the development of simplified, synthetically accessible analogs of the bryostatins."
06/09/1998 - "The bryostatins are a unique family of emerging cancer chemotherapeutic candidates isolated from marine bryozoa. "
11/01/1987 - "The macrocyclic lactone bryostatins, isolated from marine bryozoans, have been found to be strong inhibitors of e.g., the P 388 murine lymphocyte leukemia cell line and in vivo systems. "
01/15/1988 - "In intact cells, the bryostatins induce some phorbol ester responses, such as neutrophil activation, but paradoxically they not only fail to induce other responses, e.g., differentiation in HL-60 promyelocytic leukemia cells, but actually block response to the phorbol esters. "
06/15/1989 - "Comparison of effects of bryostatins 1 and 2 and 12-O-tetradecanoylphorbol-13-acetate on protein kinase C activity in A549 human lung carcinoma cells."
01/15/1989 - "Effects of activators of protein kinase C, including bryostatins 1 and 2, on the growth of A549 human lung carcinoma cells."
|5.||Pituitary Neoplasms (Pituitary Adenoma)
|1.||Protein Kinase C
|3.||Staphylococcal Protein A (A, Protein)
|6.||Immunologic Factors (Immunomodulators)
|8.||Epstein-Barr virus early antigen