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Type 5 Cyclic Nucleotide Phosphodiesterases

A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in vascular tissue and plays an important role in regulating VASCULAR SMOOTH MUSCLE contraction.
Also Known As:
Cyclic Nucleotide Phosphodiesterases, Type 5; PDE5 Phosphodiesterases; Phosphodiesterase 5; Phosphodiesterase V; Phosphodiesterase-5; cGMP-Binding, cGMP-Specific 3',5'-cyclic Nucleotide Phosphodiesterase; Phosphodiesterases, PDE5
Networked: 615 relevant articles (68 outcomes, 70 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kukreja, Rakesh C: 19 articles (03/2015 - 01/2005)
2. Kloner, Robert A: 13 articles (06/2013 - 07/2003)
3. Das, Anindita: 11 articles (03/2015 - 04/2005)
4. Salloum, Fadi N: 10 articles (03/2015 - 02/2007)
5. Guazzi, Marco: 9 articles (01/2013 - 12/2004)
6. Xi, Lei: 7 articles (03/2015 - 04/2005)
7. Dent, Paul: 5 articles (09/2015 - 10/2010)
8. Steinhorn, Robin H: 5 articles (06/2015 - 02/2008)
9. Farrow, Kathryn N: 5 articles (06/2015 - 02/2008)
10. Hoke, Nicholas N: 5 articles (12/2014 - 09/2009)

Related Diseases

1. Erectile Dysfunction
2. Heart Failure
3. Hypertension (High Blood Pressure)
4. Pulmonary Hypertension (Ayerza Syndrome)
5. Reperfusion Injury

Related Drugs and Biologics

1. sildenafil (Viagra)
2. vardenafil (Levitra)
3. tadalafil (Cialis)
4. Phosphodiesterase 5 Inhibitors
5. 5'-Guanylic Acid (GMP)
6. udenafil
7. Cyclic GMP
8. riociguat
9. tebufenozide (Mimic)
10. 3-nitropropionic acid

Related Therapies and Procedures

1. Prostatectomy (Retropubic Prostatectomy)
2. Liver Transplantation
3. Transplants (Transplant)
4. Transplantation (Transplant Recipients)
5. Drug Therapy (Chemotherapy)